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RNA-Seq 관련 논문 및 바이오뉴스(2026년 11월)

이바이오젠

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Latest Papers(RNA-Seq Part)
1. Cystine Restriction Alleviates T-cell Exhaustion and Enhances CAR T-cell Potency
Pan X et al. Cancer Res. 2026 Oct 15;86(20):5147-5166. doi: 10.1158/0008-5472.CAN-25-4375.
 
2. Molecular Consequences and Targeting of PPM1D Overexpression in Myeloproliferative Neoplasms
Mia MB et al. Blood. 2026 Oct 13:blood.2025030377. doi: 10.1182/blood.2025030377. Online ahead of print.
 
3. Comprehensive lineage tracing maps the landscape of cell fate decisions in mouse embryogenesis
Colgan WN et al. Cell. 2026 Oct 29;189(22):7154-7176.e20. doi: 10.1016/j.cell.2026.09.050. Epub 2026 Oct 8.
 
4. C1qc Mediates Blood-Brain Barrier Disruption in a Mouse Model of Intracerebral Haemorrhage Through Microglia-Derived Migrasomes
Li M et al. J Extracell Vesicles. 2026 Oct;15(10):e70377. doi: 10.1002/jev2.70377.
 
5. Mapping transcriptional responses to cellular perturbations with RNA fingerprinting
Grabski IN et al. Cell. 2026 Oct 9:S0092-8674(26)01119-0. doi: 10.1016/j.cell.2026.09.017. Online ahead of print.
 
6. Multi-omic profiling of cardiomyocyte ageing and functional decline
Yucel D et al. Cardiovasc Res. 2026 Oct 10;122(14):2009-2023. doi: 10.1093/cvr/cvag165.
 
7. SETDB1 preferentially silences evolutionarily young retroelements
Cenik BK et al. Proc Natl Acad Sci U S A. 2026 Oct 13;123(41):e2606713123. doi: 10.1073/pnas.2606713123. Epub 2026 Oct 9.
 
8. Inducing CD8(+) Tregs Limits Atherosclerosis via Notch-Mediated VSMC Quiescence
Gao W et al. Circ Res. 2026 Oct 9;139(9):e328918. doi: 10.1161/CIRCRESAHA.126.328918. Epub 2026 Sep 9.
 
9. Genome shock in a migratory songbird hybrid zone
Termignoni-Garcia F et al. Mol Biol Evol. 2026 Oct 28:msag266. doi: 10.1093/molbev/msag266. Online ahead of print.
 
10. SUMO2 deletion changes chromatin accessibility and enhances cytotoxic T cell activation and tumor infiltration
Neranjan Tharuka MD et al. Sci Adv. 2026 Oct 9;12(41):eaef2217. doi: 10.1126/sciadv.aef2217. Epub 2026 Oct 9.
 
11. Combining pro-resolving therapy with cyclosporine A restores immune homeostasis and reduces toxicity in autoimmune bone marrow failure
Grazda R et al. Cell Rep Med. 2026 Oct 20;7(10):103074. doi: 10.1016/j.xcrm.2026.103074. Epub 2026 Sep 24.
 
12. Si-scRNA-seq: Enabling ambient-stable single-cell transcriptomics through spatially confined biosilicification
Zhou L et al. Proc Natl Acad Sci U S A. 2026 Oct 27;123(43):e2617730123. doi: 10.1073/pnas.2617730123. Epub 2026 Oct 23.
 
13. Whole-transcriptome single-cell spatial landscape of instability in human carotid atherosclerosis
Byun JH et al. Cardiovasc Res. 2026 Oct 26:cvag253. doi: 10.1093/cvr/cvag253. Online ahead of print.
 
14. CDState Resolves Malignant Cell Heterogeneity from Bulk Tumor RNA Sequencing Data
Kraft A et al. Cancer Res. 2026 Oct 15;86(20):5023-5042. doi: 10.1158/0008-5472.CAN-25-4102.
 
15. Systematic profiling of AGO2-associated circRNAs and functional investigation reveal circN4BP2L2 as a survival-promoting regulator in T-ALL
Drobna-Sledzinska M et al. Leukemia. 2026 Oct;40(10):2223-2235. doi: 10.1038/s41375-026-03033-x. Epub 2026 Jul 27.
 
16. In vivo DNA damage protection during cell migration across confining embryonic tissue environments
Häkkinen HM et al. Nat Cell Biol. 2026 Oct;28(10):2088-2105. doi: 10.1038/s41556-026-02065-w. Epub 2026 Oct 9.
 
17. Intron retention regulates STAT2 function and associates with immunotherapy response in lung cancer
Englander RP et al. Science. 2026 Oct 22;394(6822):eaea7156. doi: 10.1126/science.aea7156. Epub 2026 Oct 22.
 
18. FOSL1-associated condensates modulate superenhancer-mediated selected IL-1 family gene activation in psoriasis
Qiu Y et al. Sci Adv. 2026 Oct 30;12(44):eaeh6541. doi: 10.1126/sciadv.aeh6541. Epub 2026 Oct 28.
 
19. Distinct chromatin landscapes dictate resident cardiac macrophage lifecycles and functions
Wong A et al. Cardiovasc Res. 2026 Oct 6:cvag215. doi: 10.1093/cvr/cvag215. Online ahead of print.
 
20. Genome reorganisation and expansion shape 3D genome architecture and define a distinct regulatory landscape in coleoid cephalopods
Rogers TF et al. Nat Commun. 2026 Oct 9;17(1):10319. doi: 10.1038/s41467-026-77625-7.
 
21. Uncovering combination therapies for immune-mediated inflammatory diseases through systems biology analysis on longitudinal patient data
Martínez-Mateu SH et al. Cell Rep Med. 2026 Oct 20;7(10):103026. doi: 10.1016/j.xcrm.2026.103026. Epub 2026 Sep 11.
 
22. TEDEdb: A multicohort analysis and resource for transposable element differential expression in cancer
Calendo G et al. Proc Natl Acad Sci U S A. 2026 Nov 3;123(44):e2615533123. doi: 10.1073/pnas.2615533123. Epub 2026 Oct 28.
 
23. STAG2 mutations fine-tune the ALK-driven oncogenic program in ALK-positive anaplastic large cell lymphoma
Borry R et al. Blood. 2026 Oct 5:blood.2025032902. doi: 10.1182/blood.2025032902. Online ahead of print.
 
24. A ubiquitin network safeguards cell identity by continuously degrading a stem cell-related translational machinery
Danial S et al. Genes Dev. 2026 Oct 27. doi: 10.1101/gad.353786.126. Online ahead of print.
 
25. Validation of Immunoscore for Prognostic Stratification in HPV-associated Oropharyngeal Cancer: An International Multicenter Study
Nguyen DH et al. Clin Cancer Res. 2026 Oct 13. doi: 10.1158/1078-0432.CCR-26-1776. Online ahead of print.
 
26. A domesticated totivirus-like tandem array undergoes interspecific transfer and asymmetric evolution
Taylor DJ et al. Mol Biol Evol. 2026 Oct 31:msag269. doi: 10.1093/molbev/msag269. Online ahead of print.
 
27. Multi-omic profiling of 85 iPSC lines from familial dementia reveals cellular diversity and regulators of organoid development
Qi L et al. Neuron. 2026 Oct 14:S0896-6273(26)00732-4. doi: 10.1016/j.neuron.2026.09.022. Online ahead of print.
 
28. circEPSTI1 regulates miR-942-5p-SERPINE1-AKT1 signaling axis to enhance dengue infection and is suppressed by Tiplaxtinin
Das N et al. Proc Natl Acad Sci U S A. 2026 Nov 3;123(44):e2602747123. doi: 10.1073/pnas.2602747123. Epub 2026 Oct 26.
 
29. Single-cell landscape of human adipose tissue reveals THBS1 as a potential driver of fibro-inflammation in metabolic disease
Jung J et al. Nat Commun. 2026 Oct 27;17(1):11136. doi: 10.1038/s41467-026-77107-w.
 
30. The NAC transcription factor SOMBRERO controls auxin gradients for columella root cap maturation and turnover
Wang P et al. Proc Natl Acad Sci U S A. 2026 Oct 13;123(41):e2615485123. doi: 10.1073/pnas.2615485123. Epub 2026 Oct 7.
 
31. Perinatal elimination of genetically aberrant human cortical neurons
Shao DD et al. Nature. 2026 Oct 28. doi: 10.1038/s41586-026-11190-3. Online ahead of print.
 
32. CD34+ myofibroblasts promote neointima formation in vein grafts by activating ferroptosis-induced smooth muscle cell phenotype switch
Xu SS et al. Cardiovasc Res. 2026 Oct 14:cvag235. doi: 10.1093/cvr/cvag235. Online ahead of print.
 
33. NAT10 governs development through the Xrp1-mediated stress response rather than its RNA acetylation activity
Wang L et al. Sci Adv. 2026 Oct 2;12(40):eaeg0399. doi: 10.1126/sciadv.aeg0399. Epub 2026 Sep 30.
 
 
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