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RNA-Seq 관련 논문 및 바이오뉴스(2026년 4월)

이바이오젠

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Latest Papers(RNA-Seq Part)
1. Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer
Campisi M et al. Cancer Cell. 2026 Mar 5:S1535-6108(26)00106-6. doi: 10.1016/j.ccell.2026.02.008. Online ahead of print.
 
2. Integration of Short- and Long-Read RNA Sequencing Enables the Discovery of Circular RNAs
Swift SZ et al. Cancer Res. 2026 Mar 2;86(5):1300-1318. doi: 10.1158/0008-5472.CAN-25-1114.
 
3. Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex
Ruf WP et al. Nat Commun. 2026 Mar 9;17(1):2406. doi: 10.1038/s41467-026-69944-6.
 
4. Atlas-guided discovery of transcription factors for T cell programming
Chung HK et al. Nature. 2026 Mar;651(8107):1077-1087. doi: 10.1038/s41586-025-09989-7. Epub 2026 Feb 4.
 
5. TRPM3 mediates spontaneous pain and mechanical allodynia in a mouse model of chronic orofacial neuropathy
Deseure K et al. Cell Rep Med. 2026 Mar 17;7(3):102645. doi: 10.1016/j.xcrm.2026.102645. Epub 2026 Mar 9.
 
6. A meta-analysis of single-nucleus expression quantitative trait loci linking genetic risk to brain disorders
Jang B et al. Nat Genet. 2026 Mar 19. doi: 10.1038/s41588-026-02541-x. Online ahead of print.
 
7. Multi-omics reveals key molecular and cellular features of advanced small cell lung cancers associated with distinct therapeutic opportunities
Nones K et al. Genome Med. 2026 Mar 17. doi: 10.1186/s13073-026-01624-y. Online ahead of print.
 
8. RUNX1 N6-methyladenosine methylation enhances cytoskeleton remodelling and boosts cardiac fibrosis
Ding JF et al. Cardiovasc Res. 2026 Mar 26;122(3):363-378. doi: 10.1093/cvr/cvag010.
 
9. Safety, Feasibility, and Pharmacodynamic Activity of Intratumoral Injections of the Agonist Anti-CD137 (4-1BB) mAb Urelumab in Combination with Nivolumab
Sanmamed MF et al. Clin Cancer Res. 2026 Mar 16;32(6):1036-1045. doi: 10.1158/1078-0432.CCR-25-2502.
 
10. Inhibition of NFAT after human uterus transplant promotes loss of tissue-resident NK cells and attendant pregnancy complications
Asiimwe R et al. Sci Transl Med. 2026 Mar 11;18(840):eadp2196. doi: 10.1126/scitranslmed.adp2196. Epub 2026 Mar 11.
 
11. HIV-seq reveals gene expression differences between HIV-transcribing cells from viremic and suppressed people with HIV
Frouard J et al. Nat Commun. 2026 Mar 3;17(1):1540. doi: 10.1038/s41467-026-68797-3.
 
12. Dynamic Reprogramming of PDGFRA-Expressing Stromal Cells Facilitates WNT-Driven Transformation by Promoting a Fetal-Like State in the Intestinal Epithelium
Pellon-Cardenas O et al. Cancer Res. 2026 Mar 5. doi: 10.1158/0008-5472.CAN-25-0101. Online ahead of print.
 
13. Single-cell RNA sequencing uncovers neutrophil clusters associated with autoimmune neuroinflammation
Wang Y et al. J Neuroinflammation. 2026 Mar 18. doi: 10.1186/s12974-026-03772-9. Online ahead of print.
 
14. KLF5 controls subtype-independent highly interactive enhancers in pancreatic cancer to regulate cell survival
Ekstrom TL et al. Sci Adv. 2026 Mar 20;12(12):eaea2106. doi: 10.1126/sciadv.aea2106. Epub 2026 Mar 18.
 
15. BCL11B enhancer hijacking by t(14;16)(q32;q24) translocation defines a novel high-risk subtype of T-ALL
Mimura K et al. Blood. 2026 Mar 5:blood.2025031466. doi: 10.1182/blood.2025031466. Online ahead of print.
 
16. SypC, a symbiont outer membrane vesicle protein, impacts the development of the squid-vibrio partnership
Kuwabara JT et al. Proc Natl Acad Sci U S A. 2026 Mar 17;123(11):e2524648123. doi: 10.1073/pnas.2524648123. Epub 2026 Mar 11.
 
17. Self-reinforcing IL-1b signaling accelerates the development and recurrence of TCF3::HLF-positive B-ALL
Suzuki A et al. Blood. 2026 Mar 3:blood.2025031521. doi: 10.1182/blood.2025031521. Online ahead of print.
 
18. Circuit and molecular mechanisms underlying incubation of methamphetamine craving in the prelimbic cortex
Shi S et al. Neuron. 2026 Mar 26:S0896-6273(26)00123-6. doi: 10.1016/j.neuron.2026.02.017. Online ahead of print.
 
19. Engineering lipid nanoparticle-stabilized emulsions for spatiotemporal mRNA delivery and enhanced T cell immunity
Zhou Y et al. Cell Rep Med. 2026 Mar 17;7(3):102667. doi: 10.1016/j.xcrm.2026.102667.
 
20. Spi-1 proto-oncogene regulates mRNA hypertranscription and malignant progression in head and neck cancer
Liu Z et al. Signal Transduct Target Ther. 2026 Mar 18;11(1):102. doi: 10.1038/s41392-026-02669-6.
 
21. PARP7 protects the lung epithelial barrier from diverse environmental threats
Jeltema D et al. Proc Natl Acad Sci U S A. 2026 Mar 10;123(10):e2525274123. doi: 10.1073/pnas.2525274123. Epub 2026 Mar 4.
 
22. Systematic evaluation of single-cell multimodal data integration enhances cell type resolution and discovery of clinically relevant states in complex tissues
Acera-Mateos M et al. Genome Biol. 2026 Mar 13;27(1):64. doi: 10.1186/s13059-026-04002-4.
 
23. Epstein-Barr virus drives nasopharyngeal carcinoma metastasis via RNA m(5)C modification of ICAM-1 mediated by NSUN2 and YBX3
Wang XZ et al. Cell Death Differ. 2026 Mar 18. doi: 10.1038/s41418-026-01719-4. Online ahead of print.
 
24. Integrated single-cell and spatial analysis reveals context-dependent myeloid-T cell interactions in response to immune checkpoint blockade in head and neck cancer
Golfinos-Owens AE et al. Clin Cancer Res. 2026 Mar 16. doi: 10.1158/1078-0432.CCR-25-2300. Online ahead of print.
 
25. Identifying clinically relevant cell state interactions in the tumor microenvironment of IDH-mutant gliomas using CSI-TME
Singh A et al. Mol Syst Biol. 2026 Mar 10. doi: 10.1038/s44320-026-00201-0. Online ahead of print.
 
26. Identification of cis-regulatory elements provides insights into tissue-specific gene regulation in the sheep genome
Xie S et al. Nat Commun. 2026 Mar 16;17(1):2413. doi: 10.1038/s41467-026-70382-7.
 
27. Multi-omics reveal vitamin D regulation of immune-gut microbiome interactions and tolerogenic pathways in inflammatory bowel disease
Gubatan J et al. Cell Rep Med. 2026 Mar 26:102703. doi: 10.1016/j.xcrm.2026.102703. Online ahead of print.
 
28. Dynamic and cell-type specific transcriptional reprogramming underlies the floral transition in the maize shoot apical meristem
Dong L et al. Genome Biol. 2026 Mar 18. doi: 10.1186/s13059-026-04033-x. Online ahead of print.
 
29. Single-cell analyses identify independent aging processes that compete to determine cellular fate in budding yeast
Hotz M et al. Proc Natl Acad Sci U S A. 2026 Mar 17;123(11):e2534452123. doi: 10.1073/pnas.2534452123. Epub 2026 Mar 11.
 
30. Suppressor of variegation 3-9 homolog 1 deficiency attenuates cardiac fibrosis and rescues heart failure through TACC2
Zhu C et al. Cardiovasc Res. 2026 Mar 20:cvag066. doi: 10.1093/cvr/cvag066. Online ahead of print.
 
31. Succinate supplementation ameliorates musculoskeletal defects caused by PLOD3 mutations in a BCARD syndrome model
Choudhary D et al. Genome Med. 2026 Mar 13;18(1):29. doi: 10.1186/s13073-026-01608-y.
 
32. Phosphorylation of SF3B1 by CDK11 orchestrates spliceosome activation via SNIP1-dependent RES complex recruitment
Gajdušková P et al. Nat Commun. 2026 Mar 29. doi: 10.1038/s41467-026-71119-2. Online ahead of print.
 
33. 2-Cys peroxiredoxins and the chaperone cpHSP70 act in concert in chloroplast biogenesis in Arabidopsis seedlings
Rodríguez-Marín F et al. Plant Cell. 2026 Mar 27:koag096. doi: 10.1093/plcell/koag096. Online ahead of print.
 
34. CCL3+ neutrophil signature predicts response to neoadjuvant toripalimab plus chemotherapy in patients with hypopharyngeal squamous cell carcinoma: A phase II trial
Chen F et al. Clin Cancer Res. 2026 Mar 12. doi: 10.1158/1078-0432.CCR-25-4096. Online ahead of print.
 
35. SREBP2 links ACSS2-dependent acetyl-CoA biosynthesis to metaboloepigenetic activation of hepatic stellate cells and liver fibrosis
Wang Y et al. Metabolism. 2026 Mar 24;179:156597. doi: 10.1016/j.metabol.2026.156597. Online ahead of print.
 
36. ImmuSeeker: deep mining of immune-related gene family signatures through lineage reconstruction
Jiang L et al. Genome Biol. 2026 Mar 26. doi: 10.1186/s13059-026-04039-5. Online ahead of print.
 
37. Microglia-mediated protection against Alzheimer's disease pathology and detrimental effects in white matter revealed by Ptpn6 deletion
Etxeberria A et al. Neuron. 2026 Mar 26:S0896-6273(26)00128-5. doi: 10.1016/j.neuron.2026.02.023. Online ahead of print.
 
38. Lessons from single cell omics: admixed American ancestry and sex confer cardiometabolic disease risk in Mexicans
Kar A et al. Genome Med. 2026 Mar 28. doi: 10.1186/s13073-026-01633-x. Online ahead of print.
 
 
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20. 암 '독가스'에 무너지던 면역세포, 방호복 입고 다시 싸운다
 
 
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