| Latest Papers(RNA-Seq Part) |
1. A triple-node heart-brain neuroimmune loop underlying myocardial infarction
Yadav S et al. Cell. 2026 Feb 5;189(3):800-817.e20. doi: 10.1016/j.cell.2025.12.058. Epub 2026 Jan 27.
2. ERRγ impedes neuroendocrine prostate cancer development
Li T et al. Genes Dev. 2026 Feb 2;40(3-4):160-184. doi: 10.1101/gad.353024.125.
3. Advances in single-cell transcriptomics: unraveling the pathogenesis of calcific aortic valve disease
Qin Z et al. Cardiovasc Res. 2026 Feb 14;121(18):2838-2859. doi: 10.1093/cvr/cvaf255.
4. The Ets2 super-enhancer modulates endothelial-mesenchymal transition during cardiac ageing
Guo Z et al. Cardiovasc Res. 2026 Feb 14;121(18):2892-2908. doi: 10.1093/cvr/cvaf242.
5. Atlas-guided discovery of transcription factors for T cell programming
Chung HK et al. Nature. 2026 Feb 4. doi: 10.1038/s41586-025-09989-7. Online ahead of print.
6. CRAGE-RB-PI-seq reveals transcriptional dynamics of plant-associated bacteria during root colonization
Honda T et al. Nat Commun. 2026 Feb 21. doi: 10.1038/s41467-026-69903-1. Online ahead of print.
7. Haplotype-resolved and near telomere-to-telomere assembly of the autotetraploid potato genome
Xiao PX et al. Genome Biol. 2026 Feb 3. doi: 10.1186/s13059-026-03980-9. Online ahead of print.
8. A systematic benchmark of high-accuracy PacBio long-read RNA sequencing for transcript-level quantification
Wissel D et al. Genome Biol. 2026 Feb 25. doi: 10.1186/s13059-026-03988-1. Online ahead of print.
9. Integrating scRNA-seq and snRNA-seq with spatial transcriptomics to unlock the xylem puzzle
Wei M et al. Genome Biol. 2026 Feb 23. doi: 10.1186/s13059-026-04007-z. Online ahead of print.
10. Single-cell transcriptomic analysis of plant quiescent center by third-generation sequencing reveals developmental trajectories
Hu G et al. Genome Biol. 2026 Feb 9. doi: 10.1186/s13059-026-03989-0. Online ahead of print.
11. Functional correction and genome integrity with duplex base editing of β-thalassemic hematopoietic stem cells
Papaioannou NY et al. Genome Biol. 2026 Feb 2. doi: 10.1186/s13059-026-03974-7. Online ahead of print.
12. Natural killer cells aggravate neuroinflammation through microglial type I interferon pathway activation after traumatic brain injury
Nie M et al. J Neuroinflammation. 2026 Feb 2;23(1):52. doi: 10.1186/s12974-026-03715-4.
13. DeCAF defines clinical fibroblast subtypes and multidimensional tumor-stroma crosstalk shaping prognosis and immunotherapy response
Peng XL et al. Cell Rep Med. 2026 Feb 17;7(2):102611. doi: 10.1016/j.xcrm.2026.102611.
14. Deep-Learning Tool ScVital Enables Species-Agnostic Integration of Cancer Cell States
Rub J et al. Cancer Res. 2026 Feb 16;86(4):858-872. doi: 10.1158/0008-5472.CAN-24-4889.
15. In vivo dual RNA-Seq uncovers key effectors of epithelial barrier disruption by an extracellular pathogen
Giraud-Gatineau A et al. Nat Commun. 2026 Feb 3. doi: 10.1038/s41467-026-69033-8. Online ahead of print.
16. The gene expression landscape of disease genes
García-González J et al. Genome Biol. 2026 Feb 9. doi: 10.1186/s13059-026-03958-7. Online ahead of print.
17. Single-cell resolution of splicing regulation in peripheral blood mononuclear cells uncovers heterogeneity-driven mechanisms underlying human complex traits
Liang Y et al. Nat Commun. 2026 Feb 11. doi: 10.1038/s41467-026-69325-z. Online ahead of print.
18. Translational buffering tunes gene expression in mice and humans
Rao S et al. Genome Biol. 2026 Feb 26. doi: 10.1186/s13059-026-04010-4. Online ahead of print.
19. Leveraging low-cost short-read sequencing: revolutionizing complex trait genetics
Ruckman SN et al. Mol Biol Evol. 2026 Feb 2;43(2):msag025. doi: 10.1093/molbev/msag025.
20. Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in MYOD1-mutant rhabdomyosarcoma
Dermawan JK et al. Sci Adv. 2026 Feb 27;12(9):eaea6453. doi: 10.1126/sciadv.aea6453. Epub 2026 Feb 27.
21. Taking the pulse of RNA polymerase II in intact tissue with PReCIS-seq
Platt S et al. Dev Cell. 2026 Feb 11;61(2):232-234. doi: 10.1016/j.devcel.2026.01.008.
22. HPV Integration in Head and Neck Cancer: Downstream Splicing Events and Expression Ratios Linked with Poor Outcomes
Li S et al. Clin Cancer Res. 2026 Feb 4;32(3):581-595. doi: 10.1158/1078-0432.CCR-25-0645.
23. B-lineage commitment is dependent on a reversible epigenetic switch
Tingvall-Gustafsson J et al. Genes Dev. 2026 Feb 2;40(3-4):233-254. doi: 10.1101/gad.353002.125.
24. Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics
Kumari B et al. Nat Commun. 2026 Feb 3;17(1):1218. doi: 10.1038/s41467-026-68774-w.
25. saseR: juggling offsets unlocks RNA-seq tools for fast and scalable differential usage, aberrant splicing and expression retrieval
Segers A et al. Genome Biol. 2026 Feb 18. doi: 10.1186/s13059-026-03973-8. Online ahead of print.
26. Dissecting reversible and irreversible single cell state transitions from gene regulatory networks
Ramirez DA et al. Mol Syst Biol. 2026 Feb 9. doi: 10.1038/s44320-026-00196-8. Online ahead of print.
27. Multi-omic Study of Cutaneous T-Cell Lymphoma Reveals Single Cell Clonal Evolution in Progression and Therapy Resistance
Dorando HK et al. Blood. 2026 Feb 9:blood.2025029012. doi: 10.1182/blood.2025029012. Online ahead of print.
28. Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease
Garg A et al. Cell. 2026 Feb 25:S0092-8674(26)00109-1. doi: 10.1016/j.cell.2026.01.022. Online ahead of print.
29. FLASH-MM: fast and scalable single-cell differential expression analysis using linear mixed-effects models
Xu C et al. Nat Commun. 2026 Feb 5. doi: 10.1038/s41467-026-69063-2. Online ahead of print.
30. Overcoming host restrictions to enable continuous passaging of GII.3 human norovirus in human intestinal enteroids
Kaur G et al. Sci Adv. 2026 Feb 6;12(6):eaeb0455. doi: 10.1126/sciadv.aeb0455. Epub 2026 Feb 4.
31. Spatial transcriptomics reveals tumor microenvironment-driven subtypes of invasive lobular carcinoma
Serra M et al. Proc Natl Acad Sci U S A. 2026 Feb 10;123(6):e2517567123. doi: 10.1073/pnas.2517567123. Epub 2026 Feb 4.
32. GCN5 drives MASLD progression through LXRα/SREBP1c signaling pathway-mediated de novo lipogenesis
Xiao HT et al. Nat Commun. 2026 Feb 16. doi: 10.1038/s41467-026-69736-y. Online ahead of print.
33. Splice isoform-perturbation coupled to single cell transcriptome profiling reveals functions of microexons in neurogenesis and autism-linked pathways
Dupas SJ et al. Nat Commun. 2026 Feb 3;17(1):1217. doi: 10.1038/s41467-025-67931-x.
34. Single-cell transcriptomics of the Drosophila ring gland identifies the SoxN-Vvl complex as a key regulator of juvenile hormone biosynthesis
Luo Y et al. Proc Natl Acad Sci U S A. 2026 Feb 10;123(6):e2520504123. doi: 10.1073/pnas.2520504123. Epub 2026 Feb 6.
35. Colonic spatial single-cell proteomics and murine models link mitochondrial dysfunction to dimeric IgA-secreting plasma cell deficiency in Crohn's disease
Raschdorf A et al. Nat Commun. 2026 Feb 12;17(1):1590. doi: 10.1038/s41467-026-69069-w.
36. Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition in metastatic TNBC
Greenwald NF et al. Nat Cancer. 2026 Feb 18. doi: 10.1038/s43018-026-01114-5. Online ahead of print.
37. Excess FGFR3 signaling in achondroplasia disrupts turnover of resting zone chondrocytes via CREB signaling
Horike N et al. Nat Commun. 2026 Feb 26;17(1):1856. doi: 10.1038/s41467-026-69507-9.
38. Targeting fused in sarcoma (FUS): a novel antisense strategy for treating idiopathic pulmonary fibrosis
Katariya BB et al. Signal Transduct Target Ther. 2026 Feb 26;11(1):70. doi: 10.1038/s41392-026-02585-9.
39. Responses of intestinal organoids to infection by Mycobacterium avium resemble symptoms observed in Crohn's disease
Hu W et al. Gut Microbes. 2026 Dec 31;18(1):2630483. doi: 10.1080/19490976.2026.2630483. Epub 2026 Feb 13.
40. Patient-Derived Lymphoma Spheroids Reveal Predictive Markers of Glofitamab Resistance in Relapsed/Refractory B-NHL
Marcoux P et al. Blood. 2026 Feb 26:blood.2025031309. doi: 10.1182/blood.2025031309. Online ahead of print.
41. Efficacy of the ATR inhibitor ceralasertib in patients with ARID1A-deficient gynecologic and other solid tumor malignancies
Zhu X et al. Clin Cancer Res. 2026 Feb 13. doi: 10.1158/1078-0432.CCR-25-4043. Online ahead of print.
42. Transcriptomic subgroups in soft tissue tumors correlate with morphologic subtype, genomic features, and outcome
Hofvander J et al. Clin Cancer Res. 2026 Feb 9. doi: 10.1158/1078-0432.CCR-25-3740. Online ahead of print.
43. Novel bacterium Enterocloster sp. M3 promotes colorectal tumorigenesis via the production of the carcinogen styrene
Zeng Y et al. Gut Microbes. 2026 Dec 31;18(1):2630481. doi: 10.1080/19490976.2026.2630481. Epub 2026 Feb 16.
44. Intranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signalling, in Aged Hippocampus
Madhu LN et al. J Extracell Vesicles. 2026 Feb;15(2):e70232. doi: 10.1002/jev2.70232.
45. Serum Response Factor (SRF) promotes actin cytoskeletal organization in adipocytes to support adaptive hypertrophic expansion and tissue remodeling during obesity in mice
So J et al. Metabolism. 2026 Feb 6;178:156548. doi: 10.1016/j.metabol.2026.156548. Online ahead of print.
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