(2020년 11월) RNA-Seq 관련 논문 및 바이오뉴스
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Recent Papers(RNA-Seq Part) |
1.
Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury. 2.
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma. 3.
Immobilization after injury alters extracellular matrix and stem cell fate. 4.
Maternal choline supplementation ameliorates Alzheimer's disease pathology by reducing brain homocysteine levels across multiple generations. 5.
Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma. 6.
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia. 7.
Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome. 8.
Genome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling. 9.
MiR130b from Schlafen4(+) MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer. 10.
Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population. 11.
In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. 12.
Single-cell RNA cap and tail sequencing (scRCAT-seq) reveals subtype-specific isoforms differing in transcript demarcation. 13.
A gene expression signature of TREM2(hi) macrophages and γδ T cells predicts immunotherapy response. 14.
Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies. 15.
LncSEA: a platform for long non-coding RNA related sets and enrichment analysis. 16.
A flexible, interpretable, and accurate approach for imputing the expression of unmeasured genes. 17.
RNA timestamps identify the age of single molecules in RNA sequencing. 18.
A Highly Scalable Method for Joint Whole-Genome Sequencing and Gene-Expression Profiling of Single Cells. 19.
Differences in post-mating transcriptional responses between conspecific and heterospecific matings in Drosophila. 20.
MARS: discovering novel cell types across heterogeneous single-cell experiments. 21.
Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer. 22.
Metabolic labeling of RNA using multiple ribonucleoside analogs enables the simultaneous evaluation of RNA synthesis and degradation rates. 23.
MeDAS: a Metazoan Developmental Alternative Splicing database. 24.
tsRBase: a comprehensive database for expression and function of tsRNAs in multiple species. 25.
Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers. 26.
PLncDB V2.0: a comprehensive encyclopedia of plant long noncoding RNAs. 27.
Stress-induced RNA-chromatin interactions promote endothelial dysfunction. 28.
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin. 29.
A mouse tissue atlas of small noncoding RNA. 30.
Transcriptional profile of platelets and iPSC-derived megakaryocytes from whole genome and RNA sequencing. 31.
Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small Cell Lung Carcinoma. 32.
The Transcription Co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation Into Enterocyte vs Secretory Lineages. 33.
Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes. 34.
Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans. 35.
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation. 36.
Clonal tracing reveals diverse patterns of response to immune checkpoint blockade. 37.
TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes. 38.
The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor. 39.
Massively parallel and time-resolved RNA sequencing in single cells with scNT-seq. 40.
Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies. 41.
Single-cell transcriptomics identifies divergent developmental lineage trajectories during human pituitary development. 42.
Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3. 43.
Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system. 44.
Lung megakaryocytes are immune modulatory cells. 45.
Y Chromosome LncRNA Are Involved in Radiation Response of Male Non-Small Cell Lung Cancer Cells. 46.
Jointly defining cell types from multiple single-cell datasets using LIGER. 47.
Defining Essential Enhancers for Pluripotent Stem Cells Using a Features-Oriented CRISPR-Cas9 Screen. 48.
Elucidation of Proteus mirabilis as a Key Bacterium in Crohn's Disease Inflammation. 49.
Transcriptome-directed analysis for Mendelian disease diagnosis overcomes limitations of conventional genomic testing. 50.
Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California. 51.
Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs. 52.
Bioinformatic analysis of RHO family of GTPases identifies RAC1 pharmacological inhibition as a new therapeutic strategy for hepatocellular carcinoma. 53.
Single-cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. 54.
Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input. 55.
HIV-1 infection activates endogenous retroviral promoters regulating antiviral gene expression. 56.
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids. 57.
High-Fidelity Drug Induced Liver Injury Screen Using Human PSC-derived Organoids. 58.
RASP: an atlas of transcriptome-wide RNA secondary structure probing data. 59.
SC2disease: a manually curated database of single-cell transcriptome for human diseases. 60.
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage. 61.
Murine interfollicular epidermal differentiation is gradualistic with GRHL3 controlling progression from stem to transition cell states. 62.
Fungal oxylipins direct programmed developmental switches in filamentous fungi. 63.
MIR2111-5 locus and shoot-accumulated mature miR2111 systemically enhance nodulation depending on HAR1 in Lotus japonicus. 64.
The mouse Gene Expression Database (GXD): 2021 update. 65.
The Bgee suite: integrated curated expression atlas and comparative transcriptomics in animals. 66.
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis. 67.
Interactions between lineage-associated transcription factors govern haematopoietic progenitor states. 68.
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis. 69.
Modeling tissue-relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels. 70.
The landscape of RNA Pol II binding reveals a stepwise transition during ZGA. 71.
Cellular taxonomy and spatial organization of the murine ventral posterior hypothalamus. 72.
Epigenomic Evaluation of Cholangiocyte TGFβ Signaling Identifies a Selective Role for Histone 3 Lysine 9 Acetylation in Biliary Fibrosis. 73.
A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells. 74.
Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types. 75.
Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4(+) T Cells in COVID-19. 76.
Aging Atlas: a multi-omics database for aging biology. |
Recent Bio-News |
1.
초파리, 다이너마이트 그리고 해커 2. 생명의 암호 교정하는 도구 만든 여성화학자 2명 올해 노벨화학상 3. 1, 2세대 징크핑거·탈렌 이어 3세대 크리스퍼 Cas9 유전자가위...가장 혁신적인 생명공학 기술 4. 단분자 검출하는 나노안테나 기술 개발 5. 장기 재생의 꿈 앞당기는 미니장기 '오가노이드' 6. 네가닥으로 꼬였다! DNA 사중나선 7. 코로나19 중증 환자, B세포 항체 정보 뒤죽박죽된다 8. "형광 신호로 장 내 염증 진단한다" 스마트 미생물 개발 9. 바이러스의 창 막는 박테리아의 방패 10. 원자력연, 희소 암 진단·치료용 방사성 동위원소 2종 생산 11. 日연구팀, 유도만능줄기 세포 이용 암 치료 첫 임상시험 12. 일차 섬모 손상된 생쥐 모델에서 심한 비만 나타나 13. 국내 연구진, 코로나19 폐손상 염증 유발 단백질 발견 14. 유전자 추적 '바코드'가 코로나19 전파와 진화 신속하게 찾아낸다 15. '생체 시계'로 스타 된 텔로미어, 암 치료제로 제2의 전성기 맞다 16. 3D 폐포 배양 기술로 코로나19 감염 기전 밝혔다 17. 팬토믹스, 심장 MRI 자동 분석 소프트웨어 식약처 인증 획득 18. 피로도 측정하는 패치형 센서 나왔다 19. 코로나19 중증 비밀 '네안데르탈인 유전자'에 있다 20. 코로나19 바이러스 안에 백신 면역보조제 돕는 물질 있다 - 위 기사는 동아사이언스(http://www.dongascience.com/)에서 제공하고 링크클릭시 해당 사이트로 이동하여 기사내용을 보실수 있습니다. |