| Latest Papers(RNA-Seq Part) |
1. Single-cell exploration of gonadal somatic cell lineage specification during human sex determination
Lardenois A et al. Dev Cell. 2025 Oct 9:S1534-5807(25)00571-4. doi: 10.1016/j.devcel.2025.09.011. Online ahead of print.
2. The gain-of-function TREM2-T96K mutation increases risk for Alzheimer's disease by impairing microglial function
Pilat DJ et al. Neuron. 2025 Oct 17:S0896-6273(25)00745-7. doi: 10.1016/j.neuron.2025.09.032. Online ahead of print.
3. Neuronal MCT2 promotes angiogenesis via lactate in the developing mouse neocortex
Lee D et al. Cell Death Differ. 2025 Oct 4. doi: 10.1038/s41418-025-01581-w. Online ahead of print.
4. Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder
Green NC et al. Nat Commun. 2025 Oct 13;16(1):9070. doi: 10.1038/s41467-025-64136-0.
5. Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD
Yang S et al. Nat Neurosci. 2025 Oct;28(10):2034-2043. doi: 10.1038/s41593-025-02039-5. Epub 2025 Aug 11.
6. Single-cell RNA-seq reveals cell type-specific molecular and genetic associations with primary open-angle glaucoma
Tian H et al. Signal Transduct Target Ther. 2025 Oct 10;10(1):338. doi: 10.1038/s41392-025-02438-x.
7. Identification of a PRDM1-regulated T cell network to regulate atherosclerotic plaque inflammation
Jin H et al. Genome Med. 2025 Oct 2;17(1):109. doi: 10.1186/s13073-025-01541-6.
8. Impaired cytotoxic function and exhausted phenotype of natural killer cells in VEXAS syndrome
Breillat P et al. Blood. 2025 Oct 16;146(16):1950-1963. doi: 10.1182/blood.2024028216.
9. Cell-type-specific RNA polymerase II activity maps in intact tissues provide a gateway to mammalian gene regulatory mechanisms in vivo
Chovatiya G et al. Dev Cell. 2025 Oct 20:S1534-5807(25)00602-1. doi: 10.1016/j.devcel.2025.09.017. Online ahead of print.
10. TDP-43 loss induces cryptic polyadenylation in ALS/FTD
Bryce-Smith S et al. Nat Neurosci. 2025 Oct 21. doi: 10.1038/s41593-025-02050-w. Online ahead of print.
11. YY1 regulates vascular resistance and blood pressure dynamics through epigenetic control of m6A RNA modifications in vascular smooth muscle cells
Ye W et al. Cardiovasc Res. 2025 Oct 24;121(12):1898-1916. doi: 10.1093/cvr/cvaf136.
12. Cytokine expression profile in the human brain of older adults
Godoy JB et al. J Neuroinflammation. 2025 Oct 3;22(1):224. doi: 10.1186/s12974-025-03552-x.
13. Mapping disease-specific vascular cell populations responsible for obliterative arterial remodelling during the development of pulmonary arterial hypertension
Cober ND et al. Cardiovasc Res. 2025 Oct 28;121(13):2095-2112. doi: 10.1093/cvr/cvaf146.
14. Histone lactylation promotes rheumatoid arthritis progression by increasing NFATc2 expression and the production of anti-lactylated histone autoantibodies
Wu G et al. Nat Commun. 2025 Oct 10;16(1):9034. doi: 10.1038/s41467-025-64096-5.
15. A pan-immunotherapy signature to predict intratumoral CD8(+) T cell expansions
Takahashi M et al. Nat Commun. 2025 Oct 20;16(1):9175. doi: 10.1038/s41467-025-64107-5.
16. Benchmarking scRNA-seq copy number variation callers
Schmid KT et al. Nat Commun. 2025 Oct 2;16(1):8777. doi: 10.1038/s41467-025-62359-9.
17. A scheduler for rhythmic gene expression
Gaidatzis D et al. Mol Syst Biol. 2025 Oct 10. doi: 10.1038/s44320-025-00155-9. Online ahead of print.
18. Reproducible processing of TCGA regulatory networks
Fanfani V et al. Gigascience. 2025 Oct 20:giaf126. doi: 10.1093/gigascience/giaf126. Online ahead of print.
19. PRDM16 Regulates Prostate Cancer Cell Dormancy and Prevents Bone Metastatic Outgrowth
Nasr MM et al. Cancer Res. 2025 Oct 17. doi: 10.1158/0008-5472.CAN-24-4809. Online ahead of print.
20. A single-cell multiomics roadmap of zebrafish spermatogenesis reveals regulatory principles of male germline formation
Burgos-Ruiz AM et al. Mol Syst Biol. 2025 Oct 14. doi: 10.1038/s44320-025-00157-7. Online ahead of print.
21. Editing of rice PSEUDO-ETIOLATION IN LIGHT microProtein genes promotes chloroplast development
Choi H et al. Plant Cell. 2025 Oct 7:koaf235. doi: 10.1093/plcell/koaf235. Online ahead of print.
22. A 'second hit' mouse model for group 2 and 3 pulmonary hypertension: combination of aortic banding and hypoxia exposure
Pallos LK et al. Cardiovasc Res. 2025 Oct 28;121(13):1986-1988. doi: 10.1093/cvr/cvaf147.
23. Oxidized LDL-induced FOXS1 mediates cholesterol transport dysfunction and inflammasome activation to drive aortic valve calcification
Jiang C et al. Cardiovasc Res. 2025 Oct 24;121(12):1941-1955. doi: 10.1093/cvr/cvaf159.
24. Reconstructing human pancreatic gene networks enhances stem cell-derived β cell induction
Yu XX et al. Dev Cell. 2025 Oct 20:S1534-5807(25)00603-3. doi: 10.1016/j.devcel.2025.09.018. Online ahead of print.
25. Deciphering splicing heterogeneity at single-cell resolution by SCSES
Wen X et al. Nat Commun. 2025 Oct 27;16(1):9459. doi: 10.1038/s41467-025-64517-5.
26. Systematic discovery of subcellular RNA patterns in the gut epithelium
Lee M et al. Genome Biol. 2025 Oct 29;26(1):374. doi: 10.1186/s13059-025-03786-1.
27. scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome
Reddy KD et al. Nat Commun. 2025 Oct 28;16(1):9494. doi: 10.1038/s41467-025-64778-0.
28. Genomic Drivers of Pyrethroid Resistance Escalation in the Malaria Vector Anopheles funestus Across Africa
Gadji M et al. Mol Biol Evol. 2025 Oct 1;42(10):msaf251. doi: 10.1093/molbev/msaf251.
29. SRSF1 is essential for pancreatic β-cell proliferation and the maintenance of glucose homeostasis in mice
You X et al. Metabolism. 2025 Oct 23:156421. doi: 10.1016/j.metabol.2025.156421. Online ahead of print.
30. Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21
Ranade SS et al. Nature. 2025 Oct 22. doi: 10.1038/s41586-025-09593-9. Online ahead of print.
31. Identification of microprotein-coding intronic polyadenylation isoforms and function in genotoxic anticancer drug response
Devaux A et al. Genome Biol. 2025 Oct 23;26(1):366. doi: 10.1186/s13059-025-03829-7.
32. ERRγ impedes neuroendocrine prostate cancer development
Li T et al. Genes Dev. 2025 Oct 29. doi: 10.1101/gad.353024.125. Online ahead of print.
33. Ex vivo modelling of human colorectal cancer liver metastasis by normothermic machine perfusion
Trebo M et al. Mol Cancer. 2025 Oct 21;24(1):264. doi: 10.1186/s12943-025-02430-7.
34. Prelimbic cortex to ventral tegmental area projection regulates early social isolation stress-potentiated heroin seeking in mice
Wang Y et al. Nat Commun. 2025 Oct 29;16(1):9541. doi: 10.1038/s41467-025-64585-7.
35. The role of FRUITFULL controlling cell cycle during early flower development revealed by time-series snRNA-seq experiments
Chen P et al. Genome Biol. 2025 Oct 27;26(1):370. doi: 10.1186/s13059-025-03831-z.
36. INTACT-based guard cell transcriptomes from a progressive drought time course reveal targets for modifying stomatal responses
van Weringh A et al. Plant Cell. 2025 Oct 8;37(10):koaf218. doi: 10.1093/plcell/koaf218.
37. GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density
Conery M et al. Genome Biol. 2025 Oct 3;26(1):331. doi: 10.1186/s13059-025-03802-4.
38. Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome
Garcia-Campos MA et al. Cell. 2025 Oct 22:S0092-8674(25)01082-7. doi: 10.1016/j.cell.2025.09.014. Online ahead of print.
39. YAP-Induced Glycolysis Drives Fibroinflammation and Disrupts Fibroblast Fidelity
Tsai CR et al. Circ Res. 2025 Oct 30. doi: 10.1161/CIRCRESAHA.125.326480. Online ahead of print.
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