| Latest Papers(RNA-Seq Part) |
1. Lithium deficiency and the onset of Alzheimer's disease
Aron L et al. Nature. 2025 Sep;645(8081):712-721. doi: 10.1038/s41586-025-09335-x. Epub 2025 Aug 6.
2. Generation of a Biliary Tract Cancer Cell Line Atlas Identifies Molecular Subtypes and Therapeutic Targets
Vijay V et al. Cancer Discov. 2025 Sep 4;15(9):1858-1882. doi: 10.1158/2159-8290.CD-24-1383.
3. Single-cell transcriptomic and genomic changes in the ageing human brain
Jeffries AM et al. Nature. 2025 Sep 3. doi: 10.1038/s41586-025-09435-8. Online ahead of print.
4. Integrated single-cell atlas of human atherosclerotic plaques
Traeuble K et al. Nat Commun. 2025 Sep 10;16(1):8255. doi: 10.1038/s41467-025-63202-x.
5. Shared metabolism between a bacterial and fungal species that reside in the human gut
Gause H et al. Proc Natl Acad Sci U S A. 2025 Sep 2;122(35):e2504785122. doi: 10.1073/pnas.2504785122. Epub 2025 Aug 25.
6. Reconstructed cell-type-specific rhythms in human brain link Alzheimer's pathology, circadian stress, and ribosomal disruption
Hollis HC et al. Neuron. 2025 Sep 3;113(17):2822-2838.e7. doi: 10.1016/j.neuron.2025.07.010. Epub 2025 Aug 6.
7. Tumor evolution and immune microenvironment dynamics in primary and relapsed mantle cell lymphoma
Wan H et al. Cell Rep Med. 2025 Sep 16;6(9):102318. doi: 10.1016/j.xcrm.2025.102318. Epub 2025 Aug 27.
8. The loss of microRNA-26b promotes aortic calcification through the regulation of cell-specific target genes
Luna Buitrago D et al. Cardiovasc Res. 2025 Sep 29;121(11):1778-1792. doi: 10.1093/cvr/cvaf117.
9. SWIFT-seq enables comprehensive single-cell transcriptomic profiling of circulating tumor cells in multiple myeloma and its precursors
Lightbody ED et al. Nat Cancer. 2025 Sep;6(9):1595-1611. doi: 10.1038/s43018-025-01006-0. Epub 2025 Aug 8.
10. The Origin, Diagnosis, and Prognosis of Oligomannose-Type Diffuse Large B-Cell Lymphoma
Tatterton DJ et al. Blood. 2025 Sep 2:blood.2025029163. doi: 10.1182/blood.2025029163. Online ahead of print.
11. Transcriptional dynamics of the oligodendrocyte lineage and its regulation by the brain erythropoietin system
Ye L et al. Nat Commun. 2025 Sep 16;16(1):8291. doi: 10.1038/s41467-025-62791-x.
12. Mature and migratory dendritic cells promote immune infiltration and response to anti-PD-1 checkpoint blockade in metastatic melanoma
Yang J et al. Nat Commun. 2025 Sep 1;16(1):8151. doi: 10.1038/s41467-025-62878-5.
13. Dysregulated RNA splicing impairs regeneration in alcohol-associated liver disease
Chembazhi UV et al. Nat Commun. 2025 Sep 10;16(1):8049. doi: 10.1038/s41467-025-63251-2.
14. Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation
Liao G et al. Immunity. 2025 Sep 12:S1074-7613(25)00372-3. doi: 10.1016/j.immuni.2025.08.009. Online ahead of print.
15. Phenotypic spectrum of cardiac conduction disturbance and cardiomyopathy linked to titin canonical splice-site variants
Ishikawa T et al. Cardiovasc Res. 2025 Sep 29;121(11):1712-1721. doi: 10.1093/cvr/cvaf135.
16. An activator of phosphatidylinositol 3-kinase alpha restores cardioprotection from ischaemia/reperfusion injury in mice with coronary atherosclerosis or insulin resistance
Golforoush P et al. Cardiovasc Res. 2025 Sep 29;121(11):1722-1733. doi: 10.1093/cvr/cvaf111.
17. Infiltrating macrophages replace Kupffer cells and play diverse roles in severe alcohol-associated hepatitis
Wang Y et al. Cell Mol Immunol. 2025 Sep 17. doi: 10.1038/s41423-025-01343-1. Online ahead of print.
18. GeneRAIN: multifaceted representation of genes via deep learning of gene expression networks
Su Z et al. Genome Biol. 2025 Sep 22;26(1):288. doi: 10.1186/s13059-025-03749-6.
19. Multiple overlapping binding sites determine transcription factor occupancy
Khetan S et al. Nature. 2025 Sep 3:10.1038/s41586-025-09472-3. doi: 10.1038/s41586-025-09472-3. Online ahead of print.
20. Single-cell nascent transcription reveals sparse genome usage and plasticity
Ma S et al. Cell. 2025 Sep 26:S0092-8674(25)01034-7. doi: 10.1016/j.cell.2025.09.003. Online ahead of print.
21. Hybrid BAG-seq: DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples
Li S et al. Genome Biol. 2025 Sep 27;26(1):314. doi: 10.1186/s13059-025-03790-5.
22. scKAN: interpretable single-cell analysis for cell-type-specific gene discovery and drug repurposing via Kolmogorov-Arnold networks
He H et al. Genome Biol. 2025 Sep 24;26(1):300. doi: 10.1186/s13059-025-03779-0.
23. Depleting IL1R2+ Tumor-Infiltrating Regulatory T Cells with an ADCC-Prone Nanobody Construct Boosts the Efficacy of Anti-PD1 Immunotherapy
Arnouk SM et al. Cancer Res. 2025 Sep 16. doi: 10.1158/0008-5472.CAN-24-3095. Online ahead of print.
24. Patient stratification reveals the molecular basis of disease co-occurrences
Urda-García B et al. Proc Natl Acad Sci U S A. 2025 Sep 2;122(35):e2421060122. doi: 10.1073/pnas.2421060122. Epub 2025 Aug 29.
25. Biomarker Analysis and Treatment Dynamics Following Preoperative Ipilimumab plus Nivolumab in Locally Advanced Urothelial Cancer from the Phase IB NABUCCO Study
Stockem CF et al. Clin Cancer Res. 2025 Sep 15;31(18):3897-3906. doi: 10.1158/1078-0432.CCR-25-0419.
26. Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness
Cosgrove BD et al. Science. 2025 Sep 25:eadl1988. doi: 10.1126/science.adl1988. Online ahead of print.
27. Uncovering phenotypic inheritance from single cells with Microcolony-seq
Faigenbaum-Romm R et al. Cell. 2025 Sep 18;188(19):5313-5331.e18. doi: 10.1016/j.cell.2025.08.001. Epub 2025 Aug 26.
28. Evolutionary loss of an antibiotic efflux pump increases Pseudomonas aeruginosa quorum sensing mediated virulence in vivo
Fernandes SE et al. Nat Commun. 2025 Sep 25;16(1):8397. doi: 10.1038/s41467-025-63284-7.
29. HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer
Xiao Y （肖毅） et al. Cell Metab. 2025 Sep 23:S1550-4131(25)00382-1. doi: 10.1016/j.cmet.2025.08.009. Online ahead of print.
30. INTACT-based guard cell transcriptomes from a progressive drought time course reveal targets for modifying stomatal responses
van Weringh A et al. Plant Cell. 2025 Sep 19:koaf218. doi: 10.1093/plcell/koaf218. Online ahead of print.
31. Nuclear respiratory factor 1 promotes cell survival in multiple myeloma under proteasome inhibition therapy
Bruno T et al. Blood. 2025 Sep 8:blood.2025028441. doi: 10.1182/blood.2025028441. Online ahead of print.
32. A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context
Durmaz Mitchell E et al. Mol Biol Evol. 2025 Sep 1;42(9):msaf209. doi: 10.1093/molbev/msaf209.
33. Single-cell atlas in the living fossil Yangtze sturgeon provides insight into the evolution of fish
Chen Y et al. Genome Biol. 2025 Sep 10;26(1):277. doi: 10.1186/s13059-025-03764-7.
34. Oxidized LDL-induced FOXS1 mediates cholesterol transport dysfunction and inflammasome activation to drive aortic valve calcification
Jiang C et al. Cardiovasc Res. 2025 Sep 24:cvaf159. doi: 10.1093/cvr/cvaf159. Online ahead of print.
35. HIV infection reprogrammes CD4+ T cells for quiescence and entry into proviral latency
Plasek Hegde LM et al. Nat Microbiol. 2025 Sep 26. doi: 10.1038/s41564-025-02128-y. Online ahead of print.
36. Codon-specific ribosome stalling reshapes translational dynamics during branched-chain amino acid starvation
Worpenberg L et al. Genome Biol. 2025 Sep 27;26(1):315. doi: 10.1186/s13059-025-03800-6.
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