Latest papers and news related to RNA-Seq(Mar. 2025) ebiogen 2025-03-31 13:59:05 view : 60 Latest Papers(RNA-Seq Part) 1. Telomemore enables single-cell analysis of cell cycle and chromatin condensationYakovenko I et al. Nucleic Acids Res. 2025 Jan 24;53(3):gkaf031. doi: 10.1093/nar/gkaf031. 2. The immunology of stroke and dementiaIadecola C et al. Immunity. 2025 Jan 14;58(1):18-39. doi: 10.1016/j.immuni.2024.12.008. 3. Glutathione accelerates the cell cycle and cellular reprogramming in plant regenerationLee LR et al. Dev Cell. 2025 Jan 3:S1534-5807(24)00758-5. doi: 10.1016/j.devcel.2024.12.019. Online ahead of print. 4. A cell atlas of the human fallopian tube throughout the menstrual cycle and menopauseWeigert M et al. Nat Commun. 2025 Jan 3;16(1):372. doi: 10.1038/s41467-024-55440-2. 5. ATLAS-seq: a microfluidic single-cell TCR screen for antigen-reactive TCRsLuo S et al. Nat Commun. 2025 Jan 2;16(1):216. doi: 10.1038/s41467-024-54675-3. 6. Benchmarking cross-species single-cell RNA-seq data integration methods: towards a cell type tree of lifeZhong H et al. Nucleic Acids Res. 2025 Jan 7;53(1):gkae1316. doi: 10.1093/nar/gkae1316. 7. Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulationLinder J et al. Nat Genet. 2025 Jan 8. doi: 10.1038/s41588-024-02053-6. Online ahead of print. 8. Single-cell RNA-seq identifies protracted mouse germline X chromosome reactivation dynamics directed by a PRC2-dependent mechanismLiu Y et al. Dev Cell. 2025 Jan 8:S1534-5807(24)00767-6. doi: 10.1016/j.devcel.2024.12.028. Online ahead of print. 9. A unified framework for cell-type-specific eQTL prioritization by integrating bulk and scRNA-seq dataYu X et al. Am J Hum Genet. 2025 Jan 9:S0002-9297(24)00460-9. doi: 10.1016/j.ajhg.2024.12.018. Online ahead of print. 10. Single cell approaches define neural stem cell niches and identify microglial ligands that can enhance precursor-mediated oligodendrogenesisWillis A et al. Cell Rep. 2025 Jan 15;44(1):115194. doi: 10.1016/j.celrep.2024.115194. Online ahead of print. 11. Transcript-specific enrichment enables profiling of rare cell states via single-cell RNA sequencingAbay T et al. Nat Genet. 2025 Jan 8. doi: 10.1038/s41588-024-02036-7. Online ahead of print. 12. Revealing microRNA regulation in single cellsMaji RK et al. Trends Genet. 2025 Jan 24:S0168-9525(24)00317-2. doi: 10.1016/j.tig.2024.12.009. Online ahead of print. 13. Orthologous marker groups reveal broad cell identity conservation across plant single-cell transcriptomesChau TN et al. Nat Commun. 2025 Jan 2;16(1):201. doi: 10.1038/s41467-024-55755-0. 14. Divergent roles of m(6)A in orchestrating brown and white adipocyte transcriptomes and systemic metabolismXiao L et al. Nat Commun. 2025 Jan 9;16(1):533. doi: 10.1038/s41467-024-55694-w. 15. Human subcutaneous and visceral adipocyte atlases uncover classical and nonclassical adipocytes and depot-specific patternsLazarescu O et al. Nat Genet. 2025 Jan 24. doi: 10.1038/s41588-024-02048-3. Online ahead of print. 16. Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell StateEmbaie BT et al. Cancer Res. 2025 Jan 14. doi: 10.1158/0008-5472.CAN-24-1507. Online ahead of print. 17. Single-cell Rapid Capture Hybridization sequencing to reliably detect isoform usage and coding mutations in targeted genesPeng H et al. Genome Res. 2025 Jan 10:gr.279322.124. doi: 10.1101/gr.279322.124. Online ahead of print. 18. inDrops-2: a flexible, versatile and cost-efficient droplet microfluidic approach for high-throughput scRNA-seq of fresh and preserved clinical samplesJuzenas S et al. Nucleic Acids Res. 2025 Jan 11;53(2):gkae1312. doi: 10.1093/nar/gkae1312. 19. Spatiotemporal dynamics of early oogenesis in pigsGe W et al. Genome Biol. 2025 Jan 2;26(1):2. doi: 10.1186/s13059-024-03464-8. 20. The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell deathGrilo Ruivo MT et al. Nat Commun. 2025 Jan 15;16(1):709. doi: 10.1038/s41467-025-56128-x. 21. Exposure to childhood maltreatment is associated with specific epigenetic patterns in spermTuulari JJ et al. Mol Psychiatry. 2025 Jan 3. doi: 10.1038/s41380-024-02872-3. Online ahead of print. 22. GATA2 links stemness to chemotherapy resistance in acute myeloid leukemiaAlikarami F et al. Blood. 2025 Jan 22:blood.2024025761. doi: 10.1182/blood.2024025761. Online ahead of print. 23. UDA-seq: universal droplet microfluidics-based combinatorial indexing for massive-scale multimodal single-cell sequencingLi Y et al. Nat Methods. 2025 Jan 20. doi: 10.1038/s41592-024-02586-y. Online ahead of print. 24. Analysis of multi-condition single-cell data with latent embedding multivariate regressionAhlmann-Eltze C et al. Nat Genet. 2025 Jan 3. doi: 10.1038/s41588-024-01996-0. Online ahead of print. 25. CCN5 suppresses injury-induced vascular restenosis by inhibiting smooth muscle cell proliferation and facilitating endothelial repair via thymosin β4 and Cd9 pathwayZhang Q et al. Eur Heart J. 2025 Jan 28:ehae911. doi: 10.1093/eurheartj/ehae911. Online ahead of print. 26. Sodium nitrite orchestrates macrophage mimicry of tongue squamous carcinoma cells to drive lymphatic metastasisLu X et al. Br J Cancer. 2025 Jan 11. doi: 10.1038/s41416-024-02923-0. Online ahead of print. 27. Sitravatinib in combination with nivolumab plus ipilimumab in patients with advanced clear cell renal cell carcinoma: a phase 1 trialMsaouel P et al. Nat Commun. 2025 Jan 10;16(1):578. doi: 10.1038/s41467-024-55642-8. 28. Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolutionWatson BR et al. Nat Commun. 2025 Jan 2;16(1):319. doi: 10.1038/s41467-024-55325-4. 29. Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesitySo J et al. Elife. 2025 Jan 13;13:RP97981. doi: 10.7554/eLife.97981. 30. Integrating representation learning, permutation, and optimization to detect lineage-related gene expression patternsSchlüter HM et al. Nat Commun. 2025 Jan 27;16(1):1062. doi: 10.1038/s41467-025-56388-7. 31. Chronic intermittent fasting impairs β cell maturation and function in adolescent miceMatta L et al. Cell Rep. 2025 Jan 18;44(2):115225. doi: 10.1016/j.celrep.2024.115225. Online ahead of print. 32. 3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesityTrang KB et al. Elife. 2025 Jan 15;13:RP95411. doi: 10.7554/eLife.95411. 33. Molecular logic for cellular specializations that initiate the auditory parallel processing pathwaysJing J et al. Nat Commun. 2025 Jan 9;16(1):489. doi: 10.1038/s41467-024-55257-z. 34. eIF3 engages with 3'-UTR termini of highly translated mRNAsMestre-Fos S et al. Elife. 2025 Jan 29;13:RP102977. doi: 10.7554/eLife.102977. 35. Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5' untranslated regionTang Z et al. Nat Commun. 2025 Jan 8;16(1):483. doi: 10.1038/s41467-024-55608-w. 36. Spatiotemporal transcriptome and metabolome landscapes of cotton somatic embryosGe X et al. Nat Commun. 2025 Jan 20;16(1):859. doi: 10.1038/s41467-025-55870-6. 37. Unraveling the transcriptomic landscape of brain vascular cells in dementia: A systematic reviewSewell M et al. Alzheimers Dement. 2025 Jan 14. doi: 10.1002/alz.14512. Online ahead of print. 38. Long somatic DNA-repeat expansion drives neurodegeneration in Huntington's diseaseHandsaker RE et al. Cell. 2025 Jan 16:S0092-8674(24)01379-5. doi: 10.1016/j.cell.2024.11.038. Online ahead of print. 39. Inhibition of IFITM3 in cerebrovascular endothelium alleviates Alzheimer's-related phenotypesFeng Y et al. Alzheimers Dement. 2025 Jan 14:e14543. doi: 10.1002/alz.14543. Online ahead of print. 40. RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemiaKong T et al. Nat Commun. 2025 Jan 16;16(1):492. doi: 10.1038/s41467-024-55643-7. 41. Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancerKlein L et al. Nat Commun. 2025 Jan 6;16(1):335. doi: 10.1038/s41467-024-55330-7. 42. ESRP2-microRNA-122 axis promotes the postnatal onset of liver polyploidization and maturationBangru S et al. Genes Dev. 2025 Jan 10. doi: 10.1101/gad.352129.124. Online ahead of print. 43. The Human Microglia Atlas (HuMicA) unravels changes in disease-associated microglia subsets across neurodegenerative conditionsMartins-Ferreira R et al. Nat Commun. 2025 Jan 16;16(1):739. doi: 10.1038/s41467-025-56124-1. 44. Opposing roles for Bmp signalling during the development of electrosensory lateral line organsCampbell AS et al. Elife. 2025 Jan 2;14:e99798. doi: 10.7554/eLife.99798. Online ahead of print. 45. Tumor initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in miceChen S et al. J Clin Invest. 2025 Jan 7:e180893. doi: 10.1172/JCI180893. Online ahead of print. 46. TRMT1L-catalyzed m(2)(2)G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stressHwang SP et al. Cell Rep. 2025 Jan 8;44(1):115167. doi: 10.1016/j.celrep.2024.115167. Online ahead of print. 47. Genetic variation in IL-4 activated tissue resident macrophages determines strain-specific synergistic responses to LPS epigeneticallyZhao M et al. Nat Commun. 2025 Jan 25;16(1):1030. doi: 10.1038/s41467-025-56379-8. 48. Multi-omics-based mapping of decidualization resistance in patients with a history of severe preeclampsiaMuñoz-Blat I et al. Nat Med. 2025 Jan 7. doi: 10.1038/s41591-024-03407-7. Online ahead of print. 49. edgeR v4: powerful differential analysis of sequencing data with expanded functionality and improved support for small counts and larger datasetsChen Y et al. Nucleic Acids Res. 2025 Jan 11;53(2):gkaf018. doi: 10.1093/nar/gkaf018. 50. Dissecting tumor transcriptional heterogeneity from single-cell RNA-seq data by generalized binary covariance decompositionLiu Y et al. Nat Genet. 2025 Jan;57(1):263-273. doi: 10.1038/s41588-024-01997-z. Epub 2025 Jan 2. 51. Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor bindingGao J et al. Cancer Cell. 2025 Jan 13;43(1):122-143.e8. doi: 10.1016/j.ccell.2024.12.006. Epub 2025 Jan 2. 52. Fatty acid metabolism and the oxidative stress response support bacterial predationJain R et al. Proc Natl Acad Sci U S A. 2025 Feb 4;122(5):e2420875122. doi: 10.1073/pnas.2420875122. Epub 2025 Jan 27. 53. Hypoxia-inducible factor 2 regulates alveolar regeneration after repetitive injury in three-dimensional cellular and in vivo modelsMcCall AS et al. Sci Transl Med. 2025 Jan 8;17(780):eadk8623. doi: 10.1126/scitranslmed.adk8623. Epub 2025 Jan 8. Latest Bio-News 1. 박테리아 생존 비결 찾았다…새 항생제 나올까 2. 병원균 변종 식별법 찾았다…"감염병 대응 역량 높일 것" 3. 조류인플루엔자 '팬데믹' 위기감…mRNA 백신 개발 속도 4. 변종 조류인플루엔자 위협, 탄소배출량 정점...2025년 과학계 화두 5. 코로나19로 매주 1000명 사망…"아직 끝나지 않았다" 6. 비만치료제 '위고비' 매출 우습게 넘긴 면역항암제 개발 경쟁 치열 7. 美 최초 H5N1 조류독감 사망자 발생…위험성 의견 분분 8. 만성 비염 있으면 햇빛 많이 쬐어야…비타민D 보충 필요 9. 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