| Latest Papers(RNA-Seq Part) |
1. Mapping cell type-resolved transcriptomic profiles to patient survival in pancreatic cancer
Tang R et al. Cancer Cell. 2026 Aug 10;44(8):1623-1638.e11. doi: 10.1016/j.ccell.2026.05.012. Epub 2026 Jun 11.
2. A compendium of next-generation patient-derived models for diverse cancers
ElHarouni D et al. Nature. 2026 Aug 5. doi: 10.1038/s41586-026-10806-y. Online ahead of print.
3. Lineage plasticity driven by GATA6 loss fuels colorectal cancer metastasis
Goto S et al. Cell Stem Cell. 2026 Aug 6;33(8):1304-1323.e7. doi: 10.1016/j.stem.2026.05.013. Epub 2026 Jun 22.
4. An emergent disease-associated motor neuron state precedes cell death in ALS
Gautier O et al. Cell. 2026 Aug 6;189(16):5044-5064.e12. doi: 10.1016/j.cell.2026.05.047. Epub 2026 Jun 23.
5. A reference protein atlas of the adult mouse brain vasculature
He L et al. Proc Natl Acad Sci U S A. 2026 Aug 11;123(32):e2614173123. doi: 10.1073/pnas.2614173123. Epub 2026 Aug 4.
6. Macrophage-derived SPP1 promotes subretinal fibrosis by YAP1 phase separation in retinal pigment epithelium
Lin R et al. Metabolism. 2026 Aug;181:156648. doi: 10.1016/j.metabol.2026.156648. Epub 2026 May 19.
7. Mapping enhancer-gene regulatory interactions from single-cell data
Sheth MU et al. Nat Genet. 2026 Aug;58(8):1941-1952. doi: 10.1038/s41588-026-02695-8. Epub 2026 Aug 3.
8. Single-cell and spatial omics in liver identify cell-cell communication regulators in aging and insulin resistance
Zhao W et al. Metabolism. 2026 Aug;181:156630. doi: 10.1016/j.metabol.2026.156630. Epub 2026 May 9.
9. RNA methyltransferase 3 drives pancreatic acinar cell carcinoma growth and is a therapeutic target
Tatekawa S et al. Signal Transduct Target Ther. 2026 Aug 6;11(1):327. doi: 10.1038/s41392-026-02880-5.
10. Subtypes of neurons in the cerebellar cortex
Regehr WG et al. Neuron. 2026 Aug 7:S0896-6273(26)00572-6. doi: 10.1016/j.neuron.2026.07.017. Online ahead of print.
11. A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease
Mereu E et al. Cell Metab. 2026 Aug 12:S1550-4131(26)00296-2. doi: 10.1016/j.cmet.2026.07.023. Online ahead of print.
12. Gene expression profiles of carotid plaques differ between patients with amaurosis fugax and those with cerebral transient ischaemic attack or stroke
Lan T et al. Cardiovasc Res. 2026 Aug 14;122(11):1443-1454. doi: 10.1093/cvr/cvag116.
13. AAV-NRF2 protects retinal and choroidal vasculature in a GDF15-dependent manner in an oxidative damage model of AMD
Wang S et al. Proc Natl Acad Sci U S A. 2026 Aug 18;123(33):e2616985123. doi: 10.1073/pnas.2616985123. Epub 2026 Aug 11.
14. HSF1-UCHL1 transcriptional axis protects against MASLD via regulation of PPARα protein stability
Cao Y et al. Metabolism. 2026 Aug 10;184:156733. doi: 10.1016/j.metabol.2026.156733. Online ahead of print.
15. PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia
Cao Z et al. Leukemia. 2026 Aug 24. doi: 10.1038/s41375-026-03098-8. Online ahead of print.
16. Somatosensory nerves drive pathologic bony bar formation after physis injury through pleiotrophin signaling in mouse models
Li Z et al. Sci Transl Med. 2026 Aug 5;18(861):eadv2412. doi: 10.1126/scitranslmed.adv2412. Epub 2026 Aug 5.
17. Senescent microglia with shortened telomeres secrete soluble DLK1 to induce aging-associated hypomyelination and neuronal dysfunction
Liu B et al. Neuron. 2026 Aug 11:S0896-6273(26)00577-5. doi: 10.1016/j.neuron.2026.07.021. Online ahead of print.
18. Myeloid Activator Protein-1 Complex Contributes to Salt-Sensitive Hypertension
Ahmad T et al. Circ Res. 2026 Aug 17. doi: 10.1161/CIRCRESAHA.125.327976. Online ahead of print.
19. T cell-intrinsic AIM2 exacerbates lung inflammation in OVA-LPS- and HDM-induced asthma models
Chou WC et al. Proc Natl Acad Sci U S A. 2026 Aug 11;123(32):e2520215123. doi: 10.1073/pnas.2520215123. Epub 2026 Aug 7.
20. Mitotic MAX bookmarking drives MYC-dependent hypertranscription at TBP-bound promoters
Gonzalez I et al. Genes Dev. 2026 Aug 6. doi: 10.1101/gad.354072.126. Online ahead of print.
21. Single-cell multiomics reveals exosome-mediated reprogramming and clonotypic remodeling of T cells in triple-negative breast cancer
Rezaei Benam S et al. Signal Transduct Target Ther. 2026 Aug 20;11(1):339. doi: 10.1038/s41392-026-02784-4.
22. A novel female reproductive organ differentiates insemination and postmating responses in bedbugs
Martens BM et al. Mol Biol Evol. 2026 Aug 1;43(8):msag169. doi: 10.1093/molbev/msag169.
23. RBM39 modulates UPR signaling through alternative splicing of IRE1α/ERN1
Kim JJ et al. Genes Dev. 2026 Aug 26;40(17-18):1448-1465. doi: 10.1101/gad.353632.126.
24. Regulated HSPG Signaling Directs Epicardial Behavior to Support Cardiac Formation
Redpath AN et al. Circ Res. 2026 Aug 25. doi: 10.1161/CIRCRESAHA.125.327330. Online ahead of print.
25. Transcriptome signatures for the identification of bevacizumab responders in ovarian cancer
Zolotareva O et al. Genome Med. 2026 Aug 5;18(1):121. doi: 10.1186/s13073-026-01727-6.
26. Cell-type-specific eQTLs underlie the genetic architecture of complex traits
Chen M et al. Nature. 2026 Aug 26. doi: 10.1038/s41586-026-10577-6. Online ahead of print.
27. Selective saccular plasticity under microgravity links peripheral transcriptomic remodeling to postflight vestibular dysfunction
Abe C et al. Proc Natl Acad Sci U S A. 2026 Sep;123(35):e2605593123. doi: 10.1073/pnas.2605593123. Epub 2026 Aug 17.
28. SIX1 is required for adult cochlear sensory epithelium homeostasis and auditory function
Ma X et al. Proc Natl Acad Sci U S A. 2026 Aug 11;123(32):e2520879123. doi: 10.1073/pnas.2520879123. Epub 2026 Aug 3.
29. Early versus late JAK-STAT-IFN signaling distinguishes no rejection from subclinical to clinical TCMR after liver transplantation
Macedo C et al. Sci Transl Med. 2026 Aug 5;18(861):eaec4107. doi: 10.1126/scitranslmed.aec4107. Epub 2026 Aug 5.
30. Beta2-adrenergic stimulation by fenoterol increases energy expenditure without activating human brown adipose tissue
Füchtbauer LM et al. Cell Metab. 2026 Aug 12:S1550-4131(26)00285-8. doi: 10.1016/j.cmet.2026.07.012. Online ahead of print.
31. Oncogenic KRAS Rewires mRNA Stability and Translation through AGO2-Mediated Disruption of the miRNA pathway
Yang ZZ et al. Cancer Res. 2026 Aug 24. doi: 10.1158/0008-5472.CAN-25-1047. Online ahead of print.
32. Glycolytic enolase 1-induced H4K12 lactylation activates quiescent breast cancer stem-like cells in triple-negative breast cancer
Liu S et al. Signal Transduct Target Ther. 2026 Aug 21;11(1):341. doi: 10.1038/s41392-026-02916-w.
33. Baseline circulating and tumor γδ T cells and early circulating CD8⁺PD1⁺ expansion predict response to Atezolizumab-bevacizumab in HCC
Galy-Fauroux I et al. Clin Cancer Res. 2026 Aug 17. doi: 10.1158/1078-0432.CCR-26-1102. Online ahead of print.
34. CDK8/19 inhibition prevents adaptive resistance to CDK4/6 inhibitors in vitro and in vivo
Mack ZT et al. Cell Rep Med. 2026 Aug 19:103004. doi: 10.1016/j.xcrm.2026.103004. Online ahead of print.
35. Desmoplakin Mutations in Cardiac Fibroblasts Cause TGFβ1-Mediated Pathological Fibrogenesis in Desmoplakin Cardiomyopathy Via Beclin-1 Regulation
Wei C et al. Circ Res. 2026 Aug 19. doi: 10.1161/CIRCRESAHA.124.325512. Online ahead of print.
36. Absence of EGFR signalling in granulocytic cells relieves immunosuppression sensitising CRC metastases to immune checkpoint therapy
Moreno-Viedma V et al. Cell Death Differ. 2026 Aug 11. doi: 10.1038/s41418-026-01828-0. Online ahead of print.
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