Dataset | GSEAinput_human1_collapsed_to_symbols.GSEAinput_human1.cls.txt #B_versus_A.GSEAinput_human1.cls.txt #B_versus_A_repos |
Phenotype | GSEAinput_human1.cls.txt#B_versus_A_repos |
Upregulated in class | A |
GeneSet | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE |
Enrichment Score (ES) | -0.64508003 |
Normalized Enrichment Score (NES) | -1.9344816 |
Nominal p-value | 0.0 |
FDR q-value | 0.059337147 |
FWER p-Value | 0.403 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | WFS1 | wolframin ER transmembrane glycoprotein [Source:HGNC Symbol;Acc:HGNC:12762] | WFS1 Entrez,  Source | wolframin ER transmembrane glycoprotein [Source:HGNC Symbol;Acc:HGNC:12762] | 1244 | 0.785 | -0.0476 | No |
2 | TMEM33 | transmembrane protein 33 [Source:HGNC Symbol;Acc:HGNC:25541] | TMEM33 Entrez,  Source | transmembrane protein 33 [Source:HGNC Symbol;Acc:HGNC:25541] | 2774 | 0.409 | -0.1423 | No |
3 | COPS5 | COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc:HGNC:2240] | COPS5 Entrez,  Source | COP9 signalosome subunit 5 [Source:HGNC Symbol;Acc:HGNC:2240] | 3349 | 0.309 | -0.1677 | No |
4 | NCK1 | NCK adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:7664] | NCK1 Entrez,  Source | NCK adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:7664] | 6107 | -0.022 | -0.3850 | No |
5 | ATF6 | activating transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:791] | ATF6 Entrez,  Source | activating transcription factor 6 [Source:HGNC Symbol;Acc:HGNC:791] | 6439 | -0.054 | -0.4077 | No |
6 | BCL2L11 | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | BCL2L11 Entrez,  Source | BCL2 like 11 [Source:HGNC Symbol;Acc:HGNC:994] | 6686 | -0.080 | -0.4220 | No |
7 | ATF6B | activating transcription factor 6 beta [Source:HGNC Symbol;Acc:HGNC:2349] | ATF6B Entrez,  Source | activating transcription factor 6 beta [Source:HGNC Symbol;Acc:HGNC:2349] | 7524 | -0.179 | -0.4768 | No |
8 | BAX | "BCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]" | BAX Entrez,  Source | "BCL2 associated X, apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:959]" | 7792 | -0.208 | -0.4845 | No |
9 | DAB2IP | DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294] | DAB2IP Entrez,  Source | DAB2 interacting protein [Source:HGNC Symbol;Acc:HGNC:17294] | 8030 | -0.239 | -0.4877 | No |
10 | XBP1 | X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801] | XBP1 Entrez,  Source | X-box binding protein 1 [Source:HGNC Symbol;Acc:HGNC:12801] | 8148 | -0.253 | -0.4806 | No |
11 | BOK | BCL2 family apoptosis regulator BOK [Source:HGNC Symbol;Acc:HGNC:1087] | BOK Entrez,  Source | BCL2 family apoptosis regulator BOK [Source:HGNC Symbol;Acc:HGNC:1087] | 8687 | -0.328 | -0.5019 | No |
12 | ERN1 | endoplasmic reticulum to nucleus signaling 1 [Source:HGNC Symbol;Acc:HGNC:3449] | ERN1 Entrez,  Source | endoplasmic reticulum to nucleus signaling 1 [Source:HGNC Symbol;Acc:HGNC:3449] | 9444 | -0.439 | -0.5333 | No |
13 | NCK2 | NCK adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:7665] | NCK2 Entrez,  Source | NCK adaptor protein 2 [Source:HGNC Symbol;Acc:HGNC:7665] | 10854 | -0.695 | -0.5999 | Yes |
14 | RACK1 | receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399] | RACK1 Entrez,  Source | receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399] | 11127 | -0.759 | -0.5721 | Yes |
15 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | HSPA5 Entrez,  Source | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 11618 | -0.922 | -0.5510 | Yes |
16 | BFAR | bifunctional apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:17613] | BFAR Entrez,  Source | bifunctional apoptosis regulator [Source:HGNC Symbol;Acc:HGNC:17613] | 11750 | -0.980 | -0.4976 | Yes |
17 | PTPN2 | protein tyrosine phosphatase non-receptor type 2 [Source:HGNC Symbol;Acc:HGNC:9650] | PTPN2 Entrez,  Source | protein tyrosine phosphatase non-receptor type 2 [Source:HGNC Symbol;Acc:HGNC:9650] | 11781 | -0.993 | -0.4354 | Yes |
18 | BAK1 | BCL2 antagonist/killer 1 [Source:HGNC Symbol;Acc:HGNC:949] | BAK1 Entrez,  Source | BCL2 antagonist/killer 1 [Source:HGNC Symbol;Acc:HGNC:949] | 11787 | -0.997 | -0.3710 | Yes |
19 | PIK3R1 | phosphoinositide-3-kinase regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:8979] | PIK3R1 Entrez,  Source | phosphoinositide-3-kinase regulatory subunit 1 [Source:HGNC Symbol;Acc:HGNC:8979] | 12111 | -1.194 | -0.3189 | Yes |
20 | PTPN1 | protein tyrosine phosphatase non-receptor type 1 [Source:HGNC Symbol;Acc:HGNC:9642] | PTPN1 Entrez,  Source | protein tyrosine phosphatase non-receptor type 1 [Source:HGNC Symbol;Acc:HGNC:9642] | 12139 | -1.210 | -0.2424 | Yes |
21 | PPP1R15B | protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951] | PPP1R15B Entrez,  Source | protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951] | 12144 | -1.215 | -0.1637 | Yes |
22 | PPP1R15A | protein phosphatase 1 regulatory subunit 15A [Source:HGNC Symbol;Acc:HGNC:14375] | PPP1R15A Entrez,  Source | protein phosphatase 1 regulatory subunit 15A [Source:HGNC Symbol;Acc:HGNC:14375] | 12279 | -1.328 | -0.0879 | Yes |
23 | DNAJB9 | DnaJ heat shock protein family (Hsp40) member B9 [Source:HGNC Symbol;Acc:HGNC:6968] | DNAJB9 Entrez,  Source | DnaJ heat shock protein family (Hsp40) member B9 [Source:HGNC Symbol;Acc:HGNC:6968] | 12525 | -1.778 | 0.0082 | Yes |