Dataset | GSEAinput_human1_collapsed_to_symbols.GSEAinput_human1.cls.txt #B_versus_A.GSEAinput_human1.cls.txt #B_versus_A_repos |
Phenotype | GSEAinput_human1.cls.txt#B_versus_A_repos |
Upregulated in class | B |
GeneSet | GO_PROTEIN_MONOUBIQUITINATION |
Enrichment Score (ES) | 0.45014712 |
Normalized Enrichment Score (NES) | 1.5992415 |
Nominal p-value | 0.011185682 |
FDR q-value | 0.5928799 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TRIM21 | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | TRIM21 Entrez,  Source | tripartite motif containing 21 [Source:HGNC Symbol;Acc:HGNC:11312] | 82 | 2.023 | 0.0680 | Yes |
2 | KLHL22 | kelch like family member 22 [Source:HGNC Symbol;Acc:HGNC:25888] | KLHL22 Entrez,  Source | kelch like family member 22 [Source:HGNC Symbol;Acc:HGNC:25888] | 260 | 1.504 | 0.1093 | Yes |
3 | LEO1 | "LEO1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:30401]" | LEO1 Entrez,  Source | "LEO1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:30401]" | 290 | 1.441 | 0.1601 | Yes |
4 | PEX12 | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | PEX12 Entrez,  Source | peroxisomal biogenesis factor 12 [Source:HGNC Symbol;Acc:HGNC:8854] | 371 | 1.336 | 0.2029 | Yes |
5 | RNF20 | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | RNF20 Entrez,  Source | ring finger protein 20 [Source:HGNC Symbol;Acc:HGNC:10062] | 558 | 1.154 | 0.2306 | Yes |
6 | CTR9 | "CTR9 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:16850]" | CTR9 Entrez,  Source | "CTR9 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:16850]" | 666 | 1.079 | 0.2618 | Yes |
7 | UBE2B | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | UBE2B Entrez,  Source | ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473] | 697 | 1.056 | 0.2984 | Yes |
8 | RYBP | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | RYBP Entrez,  Source | RING1 and YY1 binding protein [Source:HGNC Symbol;Acc:HGNC:10480] | 821 | 0.981 | 0.3247 | Yes |
9 | CUL4B | cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555] | CUL4B Entrez,  Source | cullin 4B [Source:HGNC Symbol;Acc:HGNC:2555] | 931 | 0.924 | 0.3501 | Yes |
10 | UBE4B | ubiquitination factor E4B [Source:HGNC Symbol;Acc:HGNC:12500] | UBE4B Entrez,  Source | ubiquitination factor E4B [Source:HGNC Symbol;Acc:HGNC:12500] | 1456 | 0.714 | 0.3347 | Yes |
11 | KLHL12 | kelch like family member 12 [Source:HGNC Symbol;Acc:HGNC:19360] | KLHL12 Entrez,  Source | kelch like family member 12 [Source:HGNC Symbol;Acc:HGNC:19360] | 1604 | 0.667 | 0.3476 | Yes |
12 | CUL3 | cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553] | CUL3 Entrez,  Source | cullin 3 [Source:HGNC Symbol;Acc:HGNC:2553] | 1647 | 0.658 | 0.3685 | Yes |
13 | TOPORS | TOP1 binding arginine/serine rich protein [Source:HGNC Symbol;Acc:HGNC:21653] | TOPORS Entrez,  Source | TOP1 binding arginine/serine rich protein [Source:HGNC Symbol;Acc:HGNC:21653] | 1760 | 0.626 | 0.3827 | Yes |
14 | UBE2W | ubiquitin conjugating enzyme E2 W [Source:HGNC Symbol;Acc:HGNC:25616] | UBE2W Entrez,  Source | ubiquitin conjugating enzyme E2 W [Source:HGNC Symbol;Acc:HGNC:25616] | 1771 | 0.623 | 0.4048 | Yes |
15 | RBX1 | ring-box 1 [Source:HGNC Symbol;Acc:HGNC:9928] | RBX1 Entrez,  Source | ring-box 1 [Source:HGNC Symbol;Acc:HGNC:9928] | 2160 | 0.531 | 0.3935 | Yes |
16 | UBE2R2 | ubiquitin conjugating enzyme E2 R2 [Source:HGNC Symbol;Acc:HGNC:19907] | UBE2R2 Entrez,  Source | ubiquitin conjugating enzyme E2 R2 [Source:HGNC Symbol;Acc:HGNC:19907] | 2310 | 0.502 | 0.4002 | Yes |
17 | NEDD4 | NEDD4 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7727] | NEDD4 Entrez,  Source | NEDD4 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7727] | 2328 | 0.498 | 0.4172 | Yes |
18 | UBE2O | ubiquitin conjugating enzyme E2 O [Source:HGNC Symbol;Acc:HGNC:29554] | UBE2O Entrez,  Source | ubiquitin conjugating enzyme E2 O [Source:HGNC Symbol;Acc:HGNC:29554] | 2331 | 0.497 | 0.4353 | Yes |
19 | DTX3L | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | DTX3L Entrez,  Source | deltex E3 ubiquitin ligase 3L [Source:HGNC Symbol;Acc:HGNC:30323] | 2689 | 0.427 | 0.4226 | Yes |
20 | TRIM25 | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | TRIM25 Entrez,  Source | tripartite motif containing 25 [Source:HGNC Symbol;Acc:HGNC:12932] | 2728 | 0.417 | 0.4350 | Yes |
21 | PCGF1 | polycomb group ring finger 1 [Source:HGNC Symbol;Acc:HGNC:17615] | PCGF1 Entrez,  Source | polycomb group ring finger 1 [Source:HGNC Symbol;Acc:HGNC:17615] | 2731 | 0.416 | 0.4501 | Yes |
22 | UHRF1 | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | UHRF1 Entrez,  Source | ubiquitin like with PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:HGNC:12556] | 2921 | 0.381 | 0.4492 | No |
23 | PAF1 | "PAF1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:25459]" | PAF1 Entrez,  Source | "PAF1 homolog, Paf1/RNA polymerase II complex component [Source:HGNC Symbol;Acc:HGNC:25459]" | 3500 | 0.283 | 0.4136 | No |
24 | UBE2T | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | UBE2T Entrez,  Source | ubiquitin conjugating enzyme E2 T [Source:HGNC Symbol;Acc:HGNC:25009] | 3654 | 0.259 | 0.4110 | No |
25 | FBXL2 | F-box and leucine rich repeat protein 2 [Source:HGNC Symbol;Acc:HGNC:13598] | FBXL2 Entrez,  Source | F-box and leucine rich repeat protein 2 [Source:HGNC Symbol;Acc:HGNC:13598] | 3976 | 0.215 | 0.3934 | No |
26 | TSG101 | tumor susceptibility 101 [Source:HGNC Symbol;Acc:HGNC:15971] | TSG101 Entrez,  Source | tumor susceptibility 101 [Source:HGNC Symbol;Acc:HGNC:15971] | 4252 | 0.177 | 0.3781 | No |
27 | UBE2D3 | ubiquitin conjugating enzyme E2 D3 [Source:HGNC Symbol;Acc:HGNC:12476] | UBE2D3 Entrez,  Source | ubiquitin conjugating enzyme E2 D3 [Source:HGNC Symbol;Acc:HGNC:12476] | 5488 | 0.026 | 0.2809 | No |
28 | WAC | WW domain containing adaptor with coiled-coil [Source:HGNC Symbol;Acc:HGNC:17327] | WAC Entrez,  Source | WW domain containing adaptor with coiled-coil [Source:HGNC Symbol;Acc:HGNC:17327] | 6012 | -0.014 | 0.2399 | No |
29 | RNF40 | ring finger protein 40 [Source:HGNC Symbol;Acc:HGNC:16867] | RNF40 Entrez,  Source | ring finger protein 40 [Source:HGNC Symbol;Acc:HGNC:16867] | 6109 | -0.023 | 0.2331 | No |
30 | DDB1 | damage specific DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2717] | DDB1 Entrez,  Source | damage specific DNA binding protein 1 [Source:HGNC Symbol;Acc:HGNC:2717] | 6179 | -0.028 | 0.2286 | No |
31 | HUWE1 | "HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:30892]" | HUWE1 Entrez,  Source | "HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 [Source:HGNC Symbol;Acc:HGNC:30892]" | 6363 | -0.045 | 0.2157 | No |
32 | FANCL | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | FANCL Entrez,  Source | FA complementation group L [Source:HGNC Symbol;Acc:HGNC:20748] | 6680 | -0.079 | 0.1935 | No |
33 | RING1 | ring finger protein 1 [Source:HGNC Symbol;Acc:HGNC:10018] | RING1 Entrez,  Source | ring finger protein 1 [Source:HGNC Symbol;Acc:HGNC:10018] | 6684 | -0.079 | 0.1962 | No |
34 | CDC73 | cell division cycle 73 [Source:HGNC Symbol;Acc:HGNC:16783] | CDC73 Entrez,  Source | cell division cycle 73 [Source:HGNC Symbol;Acc:HGNC:16783] | 6917 | -0.105 | 0.1816 | No |
35 | RNF2 | ring finger protein 2 [Source:HGNC Symbol;Acc:HGNC:10061] | RNF2 Entrez,  Source | ring finger protein 2 [Source:HGNC Symbol;Acc:HGNC:10061] | 6990 | -0.113 | 0.1801 | No |
36 | SKP1 | S-phase kinase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:10899] | SKP1 Entrez,  Source | S-phase kinase associated protein 1 [Source:HGNC Symbol;Acc:HGNC:10899] | 7341 | -0.158 | 0.1581 | No |
37 | TRIM37 | tripartite motif containing 37 [Source:HGNC Symbol;Acc:HGNC:7523] | TRIM37 Entrez,  Source | tripartite motif containing 37 [Source:HGNC Symbol;Acc:HGNC:7523] | 7744 | -0.203 | 0.1336 | No |
38 | RNF168 | ring finger protein 168 [Source:HGNC Symbol;Acc:HGNC:26661] | RNF168 Entrez,  Source | ring finger protein 168 [Source:HGNC Symbol;Acc:HGNC:26661] | 8605 | -0.317 | 0.0769 | No |
39 | MGRN1 | mahogunin ring finger 1 [Source:HGNC Symbol;Acc:HGNC:20254] | MGRN1 Entrez,  Source | mahogunin ring finger 1 [Source:HGNC Symbol;Acc:HGNC:20254] | 8716 | -0.332 | 0.0804 | No |
40 | NEDD4L | NEDD4 like E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7728] | NEDD4L Entrez,  Source | NEDD4 like E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:7728] | 8723 | -0.333 | 0.0922 | No |
41 | BCOR | BCL6 corepressor [Source:HGNC Symbol;Acc:HGNC:20893] | BCOR Entrez,  Source | BCL6 corepressor [Source:HGNC Symbol;Acc:HGNC:20893] | 8739 | -0.335 | 0.1034 | No |
42 | UBE2E1 | ubiquitin conjugating enzyme E2 E1 [Source:HGNC Symbol;Acc:HGNC:12477] | UBE2E1 Entrez,  Source | ubiquitin conjugating enzyme E2 E1 [Source:HGNC Symbol;Acc:HGNC:12477] | 10495 | -0.611 | -0.0136 | No |
43 | RAD18 | RAD18 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:18278] | RAD18 Entrez,  Source | RAD18 E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:18278] | 10607 | -0.638 | 0.0011 | No |
44 | CUL1 | cullin 1 [Source:HGNC Symbol;Acc:HGNC:2551] | CUL1 Entrez,  Source | cullin 1 [Source:HGNC Symbol;Acc:HGNC:2551] | 10667 | -0.654 | 0.0205 | No |
45 | KDM2B | lysine demethylase 2B [Source:HGNC Symbol;Acc:HGNC:13610] | KDM2B Entrez,  Source | lysine demethylase 2B [Source:HGNC Symbol;Acc:HGNC:13610] | 11383 | -0.838 | -0.0054 | No |
46 | DDB2 | damage specific DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2718] | DDB2 Entrez,  Source | damage specific DNA binding protein 2 [Source:HGNC Symbol;Acc:HGNC:2718] | 11738 | -0.975 | 0.0023 | No |
47 | RNF126 | ring finger protein 126 [Source:HGNC Symbol;Acc:HGNC:21151] | RNF126 Entrez,  Source | ring finger protein 126 [Source:HGNC Symbol;Acc:HGNC:21151] | 12542 | -1.857 | 0.0069 | No |