Dataset | GSEAinput_human1_collapsed_to_symbols.GSEAinput_human1.cls.txt #B_versus_A.GSEAinput_human1.cls.txt #B_versus_A_repos |
Phenotype | GSEAinput_human1.cls.txt#B_versus_A_repos |
Upregulated in class | A |
GeneSet | GO_CYTOPLASMIC_SEQUESTERING_OF_PROTEIN |
Enrichment Score (ES) | -0.56943405 |
Normalized Enrichment Score (NES) | -1.9065549 |
Nominal p-value | 0.0019880715 |
FDR q-value | 0.042337675 |
FWER p-Value | 0.435 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | HK2 | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | HK2 Entrez,  Source | hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923] | 1575 | 0.676 | -0.0915 | No |
2 | GOPC | golgi associated PDZ and coiled-coil motif containing [Source:HGNC Symbol;Acc:HGNC:17643] | GOPC Entrez,  Source | golgi associated PDZ and coiled-coil motif containing [Source:HGNC Symbol;Acc:HGNC:17643] | 2554 | 0.452 | -0.1468 | No |
3 | KDELR3 | KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306] | KDELR3 Entrez,  Source | KDEL endoplasmic reticulum protein retention receptor 3 [Source:HGNC Symbol;Acc:HGNC:6306] | 3379 | 0.303 | -0.1971 | No |
4 | KDELR2 | KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305] | KDELR2 Entrez,  Source | KDEL endoplasmic reticulum protein retention receptor 2 [Source:HGNC Symbol;Acc:HGNC:6305] | 3721 | 0.250 | -0.2118 | No |
5 | YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta [Source:HGNC Symbol;Acc:HGNC:12849] | YWHAB Entrez,  Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta [Source:HGNC Symbol;Acc:HGNC:12849] | 3756 | 0.245 | -0.2024 | No |
6 | KEAP1 | kelch like ECH associated protein 1 [Source:HGNC Symbol;Acc:HGNC:23177] | KEAP1 Entrez,  Source | kelch like ECH associated protein 1 [Source:HGNC Symbol;Acc:HGNC:23177] | 4446 | 0.149 | -0.2497 | No |
7 | PSMD10 | "proteasome 26S subunit, non-ATPase 10 [Source:HGNC Symbol;Acc:HGNC:9555]" | PSMD10 Entrez,  Source | "proteasome 26S subunit, non-ATPase 10 [Source:HGNC Symbol;Acc:HGNC:9555]" | 4776 | 0.107 | -0.2705 | No |
8 | SRI | sorcin [Source:HGNC Symbol;Acc:HGNC:11292] | SRI Entrez,  Source | sorcin [Source:HGNC Symbol;Acc:HGNC:11292] | 5461 | 0.029 | -0.3234 | No |
9 | MXI1 | "MAX interactor 1, dimerization protein [Source:HGNC Symbol;Acc:HGNC:7534]" | MXI1 Entrez,  Source | "MAX interactor 1, dimerization protein [Source:HGNC Symbol;Acc:HGNC:7534]" | 5920 | -0.006 | -0.3595 | No |
10 | DZIP1 | DAZ interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:20908] | DZIP1 Entrez,  Source | DAZ interacting zinc finger protein 1 [Source:HGNC Symbol;Acc:HGNC:20908] | 5998 | -0.012 | -0.3650 | No |
11 | AKT1 | AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391] | AKT1 Entrez,  Source | AKT serine/threonine kinase 1 [Source:HGNC Symbol;Acc:HGNC:391] | 6248 | -0.032 | -0.3832 | No |
12 | PINK1 | PTEN induced kinase 1 [Source:HGNC Symbol;Acc:HGNC:14581] | PINK1 Entrez,  Source | PTEN induced kinase 1 [Source:HGNC Symbol;Acc:HGNC:14581] | 6515 | -0.061 | -0.4012 | No |
13 | GRIK5 | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | GRIK5 Entrez,  Source | glutamate ionotropic receptor kainate type subunit 5 [Source:HGNC Symbol;Acc:HGNC:4583] | 6620 | -0.073 | -0.4059 | No |
14 | PKD1 | "polycystin 1, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:9008]" | PKD1 Entrez,  Source | "polycystin 1, transient receptor potential channel interacting [Source:HGNC Symbol;Acc:HGNC:9008]" | 7117 | -0.130 | -0.4388 | No |
15 | PKD2 | "polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009]" | PKD2 Entrez,  Source | "polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009]" | 7438 | -0.169 | -0.4558 | No |
16 | TSPO | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | TSPO Entrez,  Source | translocator protein [Source:HGNC Symbol;Acc:HGNC:1158] | 7805 | -0.209 | -0.4745 | No |
17 | OS9 | OS9 endoplasmic reticulum lectin [Source:HGNC Symbol;Acc:HGNC:16994] | OS9 Entrez,  Source | OS9 endoplasmic reticulum lectin [Source:HGNC Symbol;Acc:HGNC:16994] | 8218 | -0.261 | -0.4943 | No |
18 | CCDC22 | coiled-coil domain containing 22 [Source:HGNC Symbol;Acc:HGNC:28909] | CCDC22 Entrez,  Source | coiled-coil domain containing 22 [Source:HGNC Symbol;Acc:HGNC:28909] | 8537 | -0.308 | -0.5043 | No |
19 | SUFU | SUFU negative regulator of hedgehog signaling [Source:HGNC Symbol;Acc:HGNC:16466] | SUFU Entrez,  Source | SUFU negative regulator of hedgehog signaling [Source:HGNC Symbol;Acc:HGNC:16466] | 8634 | -0.320 | -0.4961 | No |
20 | HK1 | hexokinase 1 [Source:HGNC Symbol;Acc:HGNC:4922] | HK1 Entrez,  Source | hexokinase 1 [Source:HGNC Symbol;Acc:HGNC:4922] | 9405 | -0.433 | -0.5357 | No |
21 | THRA | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | THRA Entrez,  Source | thyroid hormone receptor alpha [Source:HGNC Symbol;Acc:HGNC:11796] | 9428 | -0.436 | -0.5158 | No |
22 | GET4 | guided entry of tail-anchored proteins factor 4 [Source:HGNC Symbol;Acc:HGNC:21690] | GET4 Entrez,  Source | guided entry of tail-anchored proteins factor 4 [Source:HGNC Symbol;Acc:HGNC:21690] | 9583 | -0.462 | -0.5052 | No |
23 | ANKRD13C | ankyrin repeat domain 13C [Source:HGNC Symbol;Acc:HGNC:25374] | ANKRD13C Entrez,  Source | ankyrin repeat domain 13C [Source:HGNC Symbol;Acc:HGNC:25374] | 9612 | -0.467 | -0.4842 | No |
24 | LATS1 | large tumor suppressor kinase 1 [Source:HGNC Symbol;Acc:HGNC:6514] | LATS1 Entrez,  Source | large tumor suppressor kinase 1 [Source:HGNC Symbol;Acc:HGNC:6514] | 10686 | -0.658 | -0.5368 | Yes |
25 | KDELR1 | KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304] | KDELR1 Entrez,  Source | KDEL endoplasmic reticulum protein retention receptor 1 [Source:HGNC Symbol;Acc:HGNC:6304] | 10898 | -0.704 | -0.5186 | Yes |
26 | NFKBIL1 | NFKB inhibitor like 1 [Source:HGNC Symbol;Acc:HGNC:7800] | NFKBIL1 Entrez,  Source | NFKB inhibitor like 1 [Source:HGNC Symbol;Acc:HGNC:7800] | 11340 | -0.821 | -0.5129 | Yes |
27 | GPAA1 | glycosylphosphatidylinositol anchor attachment 1 [Source:HGNC Symbol;Acc:HGNC:4446] | GPAA1 Entrez,  Source | glycosylphosphatidylinositol anchor attachment 1 [Source:HGNC Symbol;Acc:HGNC:4446] | 11392 | -0.840 | -0.4753 | Yes |
28 | FLNA | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | FLNA Entrez,  Source | filamin A [Source:HGNC Symbol;Acc:HGNC:3754] | 11491 | -0.875 | -0.4397 | Yes |
29 | HSPA5 | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | HSPA5 Entrez,  Source | heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238] | 11618 | -0.922 | -0.4039 | Yes |
30 | CREB3 | cAMP responsive element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2347] | CREB3 Entrez,  Source | cAMP responsive element binding protein 3 [Source:HGNC Symbol;Acc:HGNC:2347] | 11672 | -0.953 | -0.3609 | Yes |
31 | NFKBIB | NFKB inhibitor beta [Source:HGNC Symbol;Acc:HGNC:7798] | NFKBIB Entrez,  Source | NFKB inhibitor beta [Source:HGNC Symbol;Acc:HGNC:7798] | 11978 | -1.106 | -0.3302 | Yes |
32 | FAF1 | Fas associated factor 1 [Source:HGNC Symbol;Acc:HGNC:3578] | FAF1 Entrez,  Source | Fas associated factor 1 [Source:HGNC Symbol;Acc:HGNC:3578] | 12116 | -1.195 | -0.2818 | Yes |
33 | G3BP2 | G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291] | G3BP2 Entrez,  Source | G3BP stress granule assembly factor 2 [Source:HGNC Symbol;Acc:HGNC:30291] | 12127 | -1.203 | -0.2229 | Yes |
34 | NFKBIA | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | NFKBIA Entrez,  Source | NFKB inhibitor alpha [Source:HGNC Symbol;Acc:HGNC:7797] | 12488 | -1.658 | -0.1692 | Yes |
35 | PDIA3 | protein disulfide isomerase family A member 3 [Source:HGNC Symbol;Acc:HGNC:4606] | PDIA3 Entrez,  Source | protein disulfide isomerase family A member 3 [Source:HGNC Symbol;Acc:HGNC:4606] | 12492 | -1.666 | -0.0868 | Yes |
36 | NFKBIE | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | NFKBIE Entrez,  Source | NFKB inhibitor epsilon [Source:HGNC Symbol;Acc:HGNC:7799] | 12569 | -1.968 | 0.0048 | Yes |