Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | GSEAinput_human1_collapsed_to_symbols.GSEAinput_human1.cls.txt #B_versus_A.GSEAinput_human1.cls.txt #B_versus_A_repos |
| Phenotype | GSEAinput_human1.cls.txt#B_versus_A_repos |
| Upregulated in class | A |
| GeneSet | GO_AMINOGLYCAN_CATABOLIC_PROCESS |
| Enrichment Score (ES) | -0.5771735 |
| Normalized Enrichment Score (NES) | -1.932674 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.051112004 |
| FWER p-Value | 0.408 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PGLYRP1 | peptidoglycan recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:8904] | PGLYRP1 Entrez, Source | peptidoglycan recognition protein 1 [Source:HGNC Symbol;Acc:HGNC:8904] | 836 | 0.975 | -0.0237 | No |
| 2 | CTBS | chitobiase [Source:HGNC Symbol;Acc:HGNC:2496] | CTBS Entrez, Source | chitobiase [Source:HGNC Symbol;Acc:HGNC:2496] | 967 | 0.909 | 0.0058 | No |
| 3 | IDS | iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389] | IDS Entrez, Source | iduronate 2-sulfatase [Source:HGNC Symbol;Acc:HGNC:5389] | 2605 | 0.443 | -0.1047 | No |
| 4 | SDC2 | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | SDC2 Entrez, Source | syndecan 2 [Source:HGNC Symbol;Acc:HGNC:10659] | 4144 | 0.189 | -0.2186 | No |
| 5 | SDC1 | syndecan 1 [Source:HGNC Symbol;Acc:HGNC:10658] | SDC1 Entrez, Source | syndecan 1 [Source:HGNC Symbol;Acc:HGNC:10658] | 4234 | 0.180 | -0.2178 | No |
| 6 | SLC9A1 | solute carrier family 9 member A1 [Source:HGNC Symbol;Acc:HGNC:11071] | SLC9A1 Entrez, Source | solute carrier family 9 member A1 [Source:HGNC Symbol;Acc:HGNC:11071] | 4550 | 0.134 | -0.2369 | No |
| 7 | DCN | decorin [Source:HGNC Symbol;Acc:HGNC:2705] | DCN Entrez, Source | decorin [Source:HGNC Symbol;Acc:HGNC:2705] | 4660 | 0.121 | -0.2402 | No |
| 8 | FGF2 | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | FGF2 Entrez, Source | fibroblast growth factor 2 [Source:HGNC Symbol;Acc:HGNC:3676] | 4858 | 0.097 | -0.2517 | No |
| 9 | LUM | lumican [Source:HGNC Symbol;Acc:HGNC:6724] | LUM Entrez, Source | lumican [Source:HGNC Symbol;Acc:HGNC:6724] | 5067 | 0.070 | -0.2651 | No |
| 10 | GPC1 | glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449] | GPC1 Entrez, Source | glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449] | 5231 | 0.054 | -0.2757 | No |
| 11 | HSPG2 | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | HSPG2 Entrez, Source | heparan sulfate proteoglycan 2 [Source:HGNC Symbol;Acc:HGNC:5273] | 5660 | 0.009 | -0.3093 | No |
| 12 | GPC6 | glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454] | GPC6 Entrez, Source | glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454] | 5794 | -0.002 | -0.3198 | No |
| 13 | HMMR | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | HMMR Entrez, Source | hyaluronan mediated motility receptor [Source:HGNC Symbol;Acc:HGNC:5012] | 6161 | -0.027 | -0.3477 | No |
| 14 | HYAL2 | hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:5321] | HYAL2 Entrez, Source | hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:5321] | 7195 | -0.141 | -0.4235 | No |
| 15 | GPC4 | glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452] | GPC4 Entrez, Source | glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452] | 7619 | -0.190 | -0.4488 | No |
| 16 | HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:26527] | HGSNAT Entrez, Source | heparan-alpha-glucosaminide N-acetyltransferase [Source:HGNC Symbol;Acc:HGNC:26527] | 8693 | -0.329 | -0.5196 | No |
| 17 | HPSE | heparanase [Source:HGNC Symbol;Acc:HGNC:5164] | HPSE Entrez, Source | heparanase [Source:HGNC Symbol;Acc:HGNC:5164] | 8940 | -0.366 | -0.5231 | No |
| 18 | NAGLU | N-acetyl-alpha-glucosaminidase [Source:HGNC Symbol;Acc:HGNC:7632] | NAGLU Entrez, Source | N-acetyl-alpha-glucosaminidase [Source:HGNC Symbol;Acc:HGNC:7632] | 9122 | -0.390 | -0.5204 | No |
| 19 | GLB1 | galactosidase beta 1 [Source:HGNC Symbol;Acc:HGNC:4298] | GLB1 Entrez, Source | galactosidase beta 1 [Source:HGNC Symbol;Acc:HGNC:4298] | 9261 | -0.411 | -0.5133 | No |
| 20 | CHP1 | calcineurin like EF-hand protein 1 [Source:HGNC Symbol;Acc:HGNC:17433] | CHP1 Entrez, Source | calcineurin like EF-hand protein 1 [Source:HGNC Symbol;Acc:HGNC:17433] | 9333 | -0.422 | -0.5005 | No |
| 21 | IDUA | alpha-L-iduronidase [Source:HGNC Symbol;Acc:HGNC:5391] | IDUA Entrez, Source | alpha-L-iduronidase [Source:HGNC Symbol;Acc:HGNC:5391] | 10300 | -0.574 | -0.5520 | Yes |
| 22 | CEMIP2 | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | CEMIP2 Entrez, Source | cell migration inducing hyaluronidase 2 [Source:HGNC Symbol;Acc:HGNC:11869] | 10585 | -0.633 | -0.5468 | Yes |
| 23 | GALNS | galactosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4122] | GALNS Entrez, Source | galactosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4122] | 10643 | -0.649 | -0.5229 | Yes |
| 24 | SDC3 | syndecan 3 [Source:HGNC Symbol;Acc:HGNC:10660] | SDC3 Entrez, Source | syndecan 3 [Source:HGNC Symbol;Acc:HGNC:10660] | 10741 | -0.669 | -0.5013 | Yes |
| 25 | FUCA1 | alpha-L-fucosidase 1 [Source:HGNC Symbol;Acc:HGNC:4006] | FUCA1 Entrez, Source | alpha-L-fucosidase 1 [Source:HGNC Symbol;Acc:HGNC:4006] | 10923 | -0.709 | -0.4846 | Yes |
| 26 | HEXB | hexosaminidase subunit beta [Source:HGNC Symbol;Acc:HGNC:4879] | HEXB Entrez, Source | hexosaminidase subunit beta [Source:HGNC Symbol;Acc:HGNC:4879] | 10924 | -0.709 | -0.4535 | Yes |
| 27 | SDC4 | syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661] | SDC4 Entrez, Source | syndecan 4 [Source:HGNC Symbol;Acc:HGNC:10661] | 11483 | -0.871 | -0.4597 | Yes |
| 28 | GNS | glucosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4422] | GNS Entrez, Source | glucosamine (N-acetyl)-6-sulfatase [Source:HGNC Symbol;Acc:HGNC:4422] | 11578 | -0.907 | -0.4274 | Yes |
| 29 | HYAL3 | hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] | HYAL3 Entrez, Source | hyaluronidase 3 [Source:HGNC Symbol;Acc:HGNC:5322] | 11701 | -0.962 | -0.3950 | Yes |
| 30 | TGFB1 | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | TGFB1 Entrez, Source | transforming growth factor beta 1 [Source:HGNC Symbol;Acc:HGNC:11766] | 11951 | -1.091 | -0.3670 | Yes |
| 31 | ARSB | arylsulfatase B [Source:HGNC Symbol;Acc:HGNC:714] | ARSB Entrez, Source | arylsulfatase B [Source:HGNC Symbol;Acc:HGNC:714] | 11991 | -1.113 | -0.3213 | Yes |
| 32 | AGRN | agrin [Source:HGNC Symbol;Acc:HGNC:329] | AGRN Entrez, Source | agrin [Source:HGNC Symbol;Acc:HGNC:329] | 12091 | -1.178 | -0.2775 | Yes |
| 33 | GUSB | glucuronidase beta [Source:HGNC Symbol;Acc:HGNC:4696] | GUSB Entrez, Source | glucuronidase beta [Source:HGNC Symbol;Acc:HGNC:4696] | 12100 | -1.188 | -0.2261 | Yes |
| 34 | HEXA | hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878] | HEXA Entrez, Source | hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878] | 12280 | -1.328 | -0.1821 | Yes |
| 35 | VCAN | versican [Source:HGNC Symbol;Acc:HGNC:2464] | VCAN Entrez, Source | versican [Source:HGNC Symbol;Acc:HGNC:2464] | 12375 | -1.439 | -0.1266 | Yes |
| 36 | CD44 | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | CD44 Entrez, Source | CD44 molecule (Indian blood group) [Source:HGNC Symbol;Acc:HGNC:1681] | 12478 | -1.637 | -0.0630 | Yes |
| 37 | SGSH | N-sulfoglucosamine sulfohydrolase [Source:HGNC Symbol;Acc:HGNC:10818] | SGSH Entrez, Source | N-sulfoglucosamine sulfohydrolase [Source:HGNC Symbol;Acc:HGNC:10818] | 12503 | -1.709 | 0.0100 | Yes |
